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Acute Kidney Injury (AKI) - Differential Diagnosis Framework

PRE-Renal AKI:
 • Hypovolemia
 • Congestion
 • Medications
 •
Acute Kidney Injury ... (AKI) - Differential ... Congestion • Medications ... Infection-mediated, Drug-induced ... #Diagnosis #nephrology
Acute Kidney Injury (AKI) - Differential Diagnosis Framework
Pre-Renal:
 • Hypovolemia, Cardiorenal, Distributive Shock, HRS, Hypercalcemia, Renal
(AKI) - Differential ... Compartment Syndrome, Medications ... Protein) • AIN: Medication ... Neurogenic Bladder (Medication ... #Diagnosis #nephrology
Medications causing Acute Kidney Injury (AKI)
Prerenal:
 • Dehydration: Diuretics
 • Altered intrarenal autoregulation: ACEIs / ARBs,
Medications causing ... decongestants) • Any drug ... #Injury #Medications ... #Drugs #pharmacology ... #differential #
Drug-Induced Acute Kidney Injury - Sites of Action Along the Nephron

#DrugInduced #AcuteKidneyInjury #AKI #Nephrology #Pathophysiology #Pharmacology
Drug-Induced Acute ... Kidney Injury - ... AcuteKidneyInjury #AKI ... #Nephrology #Pathophysiology
Interpreting Kidney Biomarkers

↑ Creatinine: 
 • AKI, CKD
 • Medications that lead to nephroprotective ↓ in
Interpreting Kidney ... Creatinine: • AKI ... , CKD • Medications ... nephroprotective ↓ in GFR • Medications ... diagnosis #laboratory #nephrology
Common causes of Acute Kidney Injury AKI - Differential Diagnosis
HEMODYNAMIC
 • Cardiac failure: Impaired forward flow,
Injury AKI - Differential ... systemic disease or drugs ... hypotension • Drugs ... Nephritis (AIN) • Drugs ... #Diagnosis #nephrology
Causes of Acute Kidney Injury (AKI) - Differential Diagnosis Algorithm
Acute Kidney Injury (AKI) - Acute increase
Causes of Acute Kidney ... syndromes • Drugs ... (E. coli) • Drugs ... Nephritis • Drugs ... #KidneyInjury #Nephrology
Causes of Acute Kidney Injury ( AKI ) - Prerenal, Renal, and Postrenal

PRE-RENAL 
Impaired perfusion: 
•
Injury ( AKI ) ... tubular necrosis • Drugs ... nephritis • Drugs ... Postrenal #Failure #Differential ... #Nephrology
Drug Induced Kidney Injury
 • Pre-Renal: NSAIDS, CNI, ACEI/ARB, IL-2 therapy, Diuretics CAR-T therapy
 • Osmotic
Drug Induced Kidney ... Glomerular Disease: Drug ... #KidneyInjury #differential ... diagnosis #algorithm #nephrology ... #Medications
Acute Kidney Injury (AKI) - Differential Diagnosis Framework
Prerenal:
 • Due to true volume loss or decreased
Acute Kidney Injury ... (AKI) - Differential ... hepatorenal, sepsis • Drugs ... #Injury #AKI #Differential ... #Diagnosis #nephrology