26 results
Localization of Renal Tubular Defects
Fanconi Syndrome: Proximal tubule
Bartter Syndrome: Thick ascending loop of Henle
Gitelman Syndrome: Distal
loop of Henle Gitelman ... Fanconi #Bartter #Gitelman ... #Localization #Nephron ... #Defects #Pathophysiology ... #Nephrology
Gitelman Syndrome Pathophysiology
Gitelman Syndrome is a rare autosomal recessive salt-losing tubulopathy with a prevalence of 1-
Gitelman Syndrome ... Pathophysiology ... delivery to distal nephron ... #Syndrome #Pathophysiology ... #nephrology #diagnosis
Hypochloremia - Differential Diagnosis Algorithm

Cause - Decreased Intake:
 • Low salt in diet
 • Exclusive D5W
Differential Diagnosis Algorithm ... - Bartter - Gitelman ... rate by tubulo-glomerular ... #Pathophysiology ... #Nephrology #Chloride
Pathophysiology of hypotonic hyponatremia

by Helbert Rondon, MD @NephroMD

#hypotonic #hyponatremia #nephrology #algorithm #Pathophysiology
Pathophysiology ... Helbert Rondon, MD @NephroMD ... #hyponatremia #nephrology ... #algorithm #Pathophysiology
Major Segments of the Nephron and their Functions 
 - Glomerulus - Formation of glomerular filtrate
Segments of the Nephron ... Functions - Glomerulus ... - Formation of glomerular ... organic acids and bases ... Segments #Function #Pathophysiology
Algorithm - Approach to the differential diagnosis of the patient presenting with overt glomerular proteinuria. CMV
Algorithm - Approach ... Nephrocalcinosis causes ... nephron loss, causing ... #Algorithm #differential ... nephrotic #syndrome #nephrology
Nephritic vs Nephrotic Syndrome

Step 1: If the patient has hematuria and/or proteinuria, think about nephrotic/nephritic syndromes.
Step
the patient have glomerular ... hematuria (RBC casts ... Syndrome #Comparison #Algorithm ... #Nephrology #Diagnosis
Hyperuricemia: Pathogenesis and Complications

 - Hypercalcemia (due to diseases like Sarcoidosis and Hyperparathyroidism) -> Accumulation of
arteriole in the nephron ... -> Decr Glomerular ... tubule in the nephron ... Release of purine bases ... Hyperuricemia #Pathophysiology
Hypokalemia - Differential Diagnosis Algorithm
Extra-renal Losses:
 • Normal Acid-Base: Low intake
 • Metabolic acidosis: Gl tract
Differential Diagnosis Algorithm ... Bartter syndrome, Gitelman ... Differential #Diagnosis #Algorithm ... #causes #potassium ... #low #nephrology
Hematuria Workup and Diagnosis Algorithm
 • Confirm hematuria → Urinalysis >3 RBCs/HPF, exclude mimics, repeat testing
and Diagnosis Algorithm ... • Evidence of glomerular ... → Refer to Nephrology ... if cause not identified ... Hematuria #Diagnosis #Algorithm