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diagnosis rheumatology differential causes classification erythematosus lupus ana antibodies antinuclear arthritis bruising cerebritis cns cryoglobulinemia cryoglobulins dermatitis dermatology disease erythema
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
erythematosus (SLE ... erythematosus (SLE ... • Nucleolar: Diffuse ... Lymphoproliferative Disorders ... #rheumatology #
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm Thrombocytopenia - Quantitative Defect • Decreased Production •
Causes of Bleeding ... Differential Diagnosis Algorithm ... Sequestration Disordered ... Rare • Drugs (e.g ... #Causes #Hematology
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Lymphoproliferative Disorders ... with lymphatic system ... lymphadenopathy more diffuse ... involvement, irregular pattern ... pathophysiology #Hematology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Manifestations of Systemic ... Erythematosus (SLE ... , Seizure disorders ... inflammation, leading ... Lumbar Puncture, EEG
Nail Disorders secondary to Systemic Diseases Nail Fold Abnormality • SLE • Scleroderma • Dermatomyositis Koilonychia - Spoon-shaped
Nail Disorders secondary ... Abnormality • SLE ... halt nail growth (e.g ... #Secondary #dermatology ... Differential #Diagnosis #Algorithm
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
activate the immune system ... , leading to the ... diseases: - 10% SLE ... (e.g. systemic ... erythematosus (SLE
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... . hematologic) ... pneumonitis • Diffuse ... enteropathy, and diffuse ... vein thrombosis Hematologic
Helpful Clinical Features in Evaluating Bleeding Disorders Age of onset • Neonate - in 20% of haemophilias,
• Presence of systemic ... • Unusual pattern ... non-accidental injury Pattern ... #Bleeding #Disorders ... pediatrics #diagnosis #hematology
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... affected joint • Systemic ... Screening Tests for Diffuse ... metabolic or endocrine disorders ... Additional Tests for Diffuse
PALM RASHES Common features and patterns: 1. Color: o Red or erythematous: Common in inflammatory or allergic reactions. o Purple or purpuric:
Common features and patterns ... suggest vascular or hematologic ... depigmentation disorders ... o Peripheral patterns ... Drug Reactions: Diffuse
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