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diagnosis differential causes renal anemia arthritis bruising classification dermatitis disease eosinophil eosinophilia erythema gammopathy history laboratory lymphomas lymphoproliferative macrocytic management
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm Thrombocytopenia - Quantitative Defect • Decreased Production •
Causes of Bleeding ... Differential Diagnosis Algorithm ... Sequestration Disordered ... Rare • Drugs (e.g ... #Causes #Hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Diagnosis and Workup ... - History of bleeding ... epistaxis, gingival bleeding ... function test, ANA (e.g ... #hematology
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Eosinophil Disorders ... Testing Algorithm ... evaluation or workup ... signs or symptoms (eg ... #diagnosis #hematology
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Lymphoproliferative Disorders ... Differential Diagnosis Algorithm ... lymphadenopathy more diffuse ... involvement, irregular pattern ... pathophysiology #Hematology
Anemia Diagnostic Algorithm Mean corpuscular (cell) volume (MCV): Average RBC size. Under 80 = microcytic. Between 80-95
Anemia Diagnostic Algorithm ... (BM) ablative disorders ... of substrate (e.g ... #Diagnosis #Workup ... #Hematology #Microcytic
Helpful Clinical Features in Evaluating Bleeding Disorders Age of onset • Neonate - in 20% of haemophilias,
Drug history, e.g ... anticoagulants • Unusual pattern ... non-accidental injury Pattern ... #Bleeding #Disorders ... pediatrics #diagnosis #hematology
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
mononeuritis multiplex WORKUP ... recent DAN) • EMG ... to diffuse alveolar ... hemorrhage (DAH) • Diffuse ... • IF staining patterns
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... Screening Tests for Diffuse ... metabolic or endocrine disorders ... Additional Tests for Diffuse ... Arthritis #laboratory #workup
PALM RASHES Common features and patterns: 1. Color: o Red or erythematous: Common in inflammatory or allergic reactions. o Purple or purpuric:
Common features and patterns ... suggest vascular or hematologic ... depigmentation disorders ... o Peripheral patterns ... Drug Reactions: Diffuse
Monoclonal Gammopathy of Renal Significance (MGRS) MGRS • MGRS refers to kidney disease caused by nephrotoxic monoclonal immunoglobulins
or plasma cell disorder ... meet criteria for hematologic ... Why Does MGRS Matter ... or evolve into hematologic ... Diagnostic Workup
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