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diagnosis rheumatology vasculitis differential anca clinical endocrinology management mpo physicalexam pr3 radiology signs video aav abdomen adenomatous algorithm ana aneurysm
The Cell Cycle The cell cycle is the series of tightly regulated steps that controls cell growth
Both Rb and p53 ... in the case of p53 ... notice how much p53 ... Thats right, p53 ... Yes, its p53 (and
ANCA-Associated Vasculitis A group of necrotizing, small-vessel vasculitis without immune complex deposition. Complement levels are normal due
associated with PR3 ... involvement - PR3 ... 75-90%, rarely PR3 ... disease - MPO>PR3 ... + almost 100%, PR3
Frequency of ANCA Positivity in Different Conditions ANCA-Associated Vasculitis • GPA - PR3-ANCA 75%, MPO-ANCA 20%, 5%
Vasculitis • GPA - PR3 ... negative • MPA - PR3 ... negative • EGPA - PR3 ... positivity for MPO and PR3 ... sensitivity #MPO #PR3
#lithium #neurogenesis #neuroprotective #mood stabilizers -Neurogenesis continues to occur throughout the lifetime in human adult brains, and
excitotoxicity, p53
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
polyangiitis - MPO>PR3 ... polyangiitis - PR3 ... involvement - PR3 ... Churg-Strauss) - MPO>PR3 ... disease - MPO>PR3
Metformin Treatment in Patients With Type 2 Diabetes and Chronic Kidney Disease Stages 3A, 3B, or
Mar; 41(3): 547-553
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
proteinase 3 (PR3 ... in >90%, MPO > PR3 ... Granulomas - MPO > PR3 ... 80% (80-90% have PR3 ... proteinase 3 (PR3
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
Negative IF): • PR3
Causes of Hypercalcemia due to increased Vitamin D levels • The BIG 3:
granulomatous diseases: PR3
ANCA Associated Vasculitis (AAV) - Auto-antibodies and Differential Diagnosis MPA → usually p-ANCA GPA → usually c-ANCA EGPA →
(MPO) C-ANCA (PR3
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