37 results
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm
Thrombocytopenia - Quantitative Defect
 • Decreased Production
 •
Causes of Bleeding ... Destruction • Abnormal ... Sequestration Disordered ... Rare • Drugs (e.g ... #Hematology
Causes of Prolonged PT (INR), Prolonged PTT
 • Prolonged PT (INR), Prolonged PTT
 • Prolonged PT
Causes of Prolonged ... PT (INR) - Bleeding ... PT (INR) - No Bleeding ... #Hematology #coagulation ... #disorders
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
- History of bleeding ... epistaxis, gingival bleeding ... function test, ANA (e.g ... or if a primary hematologic ... #Workup #hematology
Causes of Neutrophilia - Increased Neutrophils - Differential Diagnosis Algorithm
Infection
 • Bacterial
 • Abscess
 • Viral
Medications
Causes of Neutrophilia ... Solid Tumour (e.g ... • Metabolic disorders ... Myeloproliferative Disorder ... #Hematology
Causes of Splenomegaly - Differential Diagnosis Algorithm
Infectious
 • Bacterial
 • Viral (EBV)
 • Parasitic
 • Fungal
Congestive
Causes of Splenomegaly ... • Thrombus (e.g ... Myeloproliferative disorders ... (eg. polycythemia ... #Hematology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Causes of Anemia ... Increased Requirement (e.g ... • Small Bowel Disorder ... Deficiency - Abnormal ... #Hematology
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Low Mean Corpuscular Volume (<80
Causes of Anemia ... Chronic Disease Normal ... 80-100 fL) • Bleeding ... Chronic Disease (e.g ... #Hematology
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Decreased WBCs
 - Decreased/NormaI
Causes of Anemia ... • Secondary (e.g ... Anemias (MAHA) - Abnormal ... Diagnosis #Algorithm #Causes ... #Hematology
Causes of Thrombocytosis - Differential Diagnosis
Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis):
 • Acute infection
 • Solid organ
Causes of Thrombocytosis ... Chronic inflammatory disorders ... (e.g. autoimmune ... Differential #Diagnosis #Causes ... #hematology #secondary
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... (usually IgG) (e.g ... lymphoproliferative disorders ... Extravascular #Causes ... differential #diagnosis #hematology