8 results
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
, coagulation disorders ... disorders CAUSES ... - Hemolytic anemia ... OF PALPABLE PURPURA ... Differential #Diagnosis #hematology
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm
Thrombocytopenia - Quantitative Defect
 • Decreased Production
 •
Causes of Bleeding ... Differential Diagnosis Algorithm ... Thrombocytopenia ... Sequestration Disordered ... #Causes #Hematology
Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
 • Artifact (redo CBC)
Autonomous:
 • Essential thrombocytosis
 • Polycythemia
Causes of Thrombocytosis ... • Rheumatic disorders ... following EtOH induced thrombocytopenia ... Iron deficiency anemia ... #Causes #Hematology
Causes of Purpura or Easy Bruising in Children

Platelet count reduced, i.e. thrombocytopenia
 - Increased platelet destruction
Causes of Purpura ... intravascular coagulation ... bypass Vascular disorders ... #Bruising #Causes ... #peds #pediatrics
Causes of Petechial Rash - Differential Diagnosis Algorithm

Pinpoint areas (less than 2 mm) of hemorrhage, which
Causes of Petechial ... hemostasis: - Thrombocytopenia ... Vasculitis - Collagen disorders ... Complete blood count coagulation ... #Causes #dermatology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
intravascular coagulation ... microangiopathy: Thrombotic thrombocytopenic ... purpura (TTP), ... lymphoproliferative disorders ... differential #diagnosis #hematology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
Petechiae • Purpura ... • Palpable variants ... Treat primary cause ... #diagnosis #causes ... treatment #management #hematology
Overall Approach to Anemia - Differential Diagnosis Algorithm

Blood Loss
 • Acute Bleed - Normocytic / Normochromic
Differential Diagnosis Algorithm ... • RBC Membrane Disorder ... RBC Metabolism Disorder ... #Classification ... #Causes #Hematology