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diagnosis differential management oncology lymphadenopathy blood focal localized product reactions syndrome classification disorders essential et leukemia leukostasis lymphomas lymphoproliferative lysis
Causes of Diffuse and Localized Lymphadenopathy - Differential Diagnosis Algorithm • Reactive (Inflammatory / Infectious) •
Causes of Diffuse ... Differential Diagnosis Algorithm ... Metastatic) #Diffuse ... Lymphadenopathy #LAD ... #Causes #Hematology
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
Causes of Diffuse ... Differential Diagnosis Algorithm ... Fatigue • Acute ... Lymphadenopathy #LAD ... #Causes #Hematology
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Causes of Thrombocytosis ... Differential Diagnosis Algorithm ... Infectious: • Acute ... effect following treatment ... #Causes #Hematology
Causes of Localized Lymphadenopathy - Differential Diagnosis Algorithm Cervical: - Anterior • Infection
Causes of Localized ... Differential Diagnosis Algorithm ... Epitrochlear (Always pathologic ... Lymphadenopathy #LAD ... #Causes #Hematology
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Differential Diagnosis Algorithm ... lymphadenopathy more diffuse ... Responsive to Treatment ... Treated Like Acute ... pathophysiology #Hematology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
high WBC count cause ... - ACS, AKI, acute ... organ damage • Treatment ... Low calcium • Treatment ... diagnosis #management #hematology
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
Rule out other causes ... and lower jaw Treatment ... TNF blockers had ... SAPHO #Syndrome #Rheumatology ... diagnosis #management #Dermatology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
, APML, CLL Acute ... infections, bone pain ... activity • ↓ LAP ... -> AML: Blast crises ... #Leukemia #Hematology
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
• Acute Hemolytic ... : Fever, flank pain ... Causes purpura & ... Transfusion Related Acute ... diagnosis #management #hematology
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
- Acute Hemolytic ... : Fever, flank pain ... Causes purpura & ... Transfusion Related Acute ... diagnosis #management #hematology
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