16 results
Antinuclear Antibody Testing - Nuclear and Cytoplasmic Patterns
Nuclear Patterns:
 • Homogeneous pattern: 
   -
Antinuclear Antibody ... phenomenon, SjS, cancer ... ARUPConsult @ARUPLabs #ANA ... #differential #diagnosis ... #rheumatology
Antinuclear Antibody Testing - Nuclear Patterns
Homogeneous pattern: 
 • SLE, SSc, AIH, JIA
 • dsDNA, chromatin,
Antinuclear Antibody ... phenomenon, SjS, cancer ... #Antinuclear #Antibody ... #differential #diagnosis ... #rheumatology
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
context of other symptoms ... : The ANA patterns ... , Interstitial Pulmonary ... #patterns #rheumatology ... #diagnosis #differential
Inflammatory Myopathies
Dermatomyositis
 • Onset: Subacute
 • Pattern: Proximal
 • CK: Up to 50X ULN
 • Autoantibodies:
Associated Features: Cancer-associated ... heliotrope, shawl sign ... : Proximal and distal ... #differential #diagnosis ... #comparison #rheumatology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
rapid onset of symptoms ... -> AML: Blast crises ... lymphoid organs When Cancer ... #Hematology #Oncology ... #Diagnosis
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
- Summary Cancer ... with no early symptoms ... Physical Exam/Signs ... #diagnosis #workup ... #oncology #hematology
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Episcleritis Signs ... and Symptoms: ... Causes: - Idiopathic ... , breast CA - Hematologic ... cutis Diagnosis
Features That Differentiate Acute Pericarditis from Myocardial Ischemia or Infarction and Pulmonary Embolism

In contrast to the
Pulmonary Embolism ... life-threatening causes ... #Signs #Presentation ... #comparison #Table ... #Diagnosis
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
without other cause ... ARDS to explain symptoms ... CXR with pulmonary ... Transfusion #Reactions #hematology ... #diagnosis #comparison
Cryofibrinogenemia Summary

Cryofibrinogenemia Epidemiology:
 • 40-70 years with a modest female predominance

Cryofibrinogenemia:
 • The precipitation of a
Cryofibrinogenemia Symptoms ... thrombophlebitis, pulmonary ... Biopsy: Typical pathologic ... #rheumatology # ... hematology