34 results
Paths to Defective Homologous Recombination DNA Repair in Breast Cancer. Each individual mutation or epigenetic aberration
Repair in Breast Cancer ... feature of breast cancer ... #Pathophys #Honc ... BreastCancer #DNARepair #NEJM
Signaling Mechanism of PD-1 and PD-L1 and Inhibition of PD-1 Signaling in Microsatellite-Instability–High Cancers. MHC1 denotes
Microsatellite-Instability–High Cancers ... Pathophysiology #Honc ... MicrosatelliteInstability #NEJM
Dermatological semiology of Cutaneous Vasculitis 

Clinicopathologic correlations
 • Purpura, papules, pustules, necrosis: involvement of small vessels
EGPA • Solid cancers ... dermatology #semiology #signs ... manifestations #pathology ... #lesions #differential
Histologic Features and Prevalence of Nonalcoholic Steatohepatitis (NASH). NASH is a potentially progressive type of nonalcoholic
primary liver cancer ... #Pathology #Epidemiology ... HCC #Prevalence #NEJM
Causes of Localized Lymphadenopathy - Differential Diagnosis Algorithm
Cervical:
 - Anterior
     • Infection
Lymphadenopathy - Differential ... , Breast) • Cancer ... Epitrochlear (Always pathologic ... Infection • Cancer ... Lymphadenopathy #LAD #Differential
Alectinib versus Crizotinib in Untreated ALK-Positive Non–Small-Cell Lung Cancer #EBM #Honc #Alectinib #Crizotinib #ALK #ALKPositive #NSCLC
Non–Small-Cell Lung Cancer ... #EBM #Honc #Alectinib ... VisualAbstract #NEJM
Approach to Headaches - Differential Diagnosis Algorithm

Red flags (PHANTOMS):
 • Pattern change, progressively worse, papilledema
 •
to Headaches - Differential ... syndrome, history of cancer ... • Meningeal signs ... Systemic symptoms and signs ... #Headache #Differential
Pulmonary Pathology and Associated Lung Ultrasound Findings
Pneumothorax:
 - No lung sliding/barcode sign
 - Lung point (hard
Pulmonary Pathology ... sliding/barcode sign ... Consolidations - "Shred" sign ... #pulmonary #differential ... #diagnosis #signs
Faget's Sign & Liebermeister's Rule
Pulse-Temperature Dissociation
EVERY 1 F RISE IN TEMPERATURE -> HR INCREASES 8-10 BPM
INFECTIOUS
Faget's Sign & Liebermeister's ... where it can help hone ... your differential ... #Fagets #Sign #Pulse ... Dissociation #diagnosis #differential
Durvalumab after Chemoradiotherapy in Stage III Non–Small-Cell Lung Cancer - Progression-free Survival in the Intention-to-Treat Population.
Non–Small-Cell Lung Cancer ... #EBM #Honc #PACIFIC ... Durvalumab #NSCLC #NEJM