82 results
Excoriated papules with honey-colored crusting were present on the abdomen, back (Panel A), arms, and legs.
Finally, skin scrapings ... #Clinical #Derm ... #Pathology #Scabies ... Microscopy #Rash #NEJM
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Adult-Onset Still's Disease ... Clinical triad ... Arthralgia/arthritis, Skin ... hemopathies, solid cancers ... management #treatment #rheumatology
Pathology - Castleman disease. 

Mediastinal mass in a younger woman.

Histologic Features of Castleman disease, hyaline vascular
Pathology - Castleman ... disease. ... vessels - Germinal center ... #Pathology #Smear ... #Microscopy #Clinical
Causes of Localized Lymphadenopathy - Differential Diagnosis Algorithm
Cervical:
 - Anterior
     • Infection
• Kikuchi Disease ... , Breast) • Cancer ... Epitrochlear (Always pathologic ... Infection • Cancer ... Algorithm #Causes #Hematology
Histologic Features and Prevalence of Nonalcoholic Steatohepatitis (NASH). NASH is a potentially progressive type of nonalcoholic
nonalcoholic fatty liver disease ... primary liver cancer ... #Pathology #Epidemiology ... HCC #Prevalence #NEJM
VEXAS (Vacuoles, E1 enzyme, X-linked, Autoinflammatory, Somatic) Syndrome
Clinical Syndrome:
 • Common Clinical Features: alveolitis, ear and
Somatic) Syndrome Clinical ... Syndrome: • Common Clinical ... nose chondritis, skin ... thromboembolic disease ... myeloid cells NEJM
Castleman's Disease and Associated Syndromes
HYALINE VASCULAR VARIANT
 • unicentric, HHV8-ve, children and young.
 • Hyalinized vessels
Castleman's Disease ... fashion- onion skin ... Atrophic erminal center ... Hyperplastic germinal center ... Variants #Diagnosis #Pathology
Plasma cell leukemia with extensive rouleaux formation. Aggressive disease & patients typically younger than other forms
Aggressive disease ... rouleaux #formation #Clinical ... #Smear #Hematology ... #Pathology
Acute Graft versus Host disease: vacuolar interface dermatitis w/ lymphoexocytosis, dyskeratotic keratinocytes, notable satellite cell necrosis.
Graft versus Host disease ... #versus #Host #disease ... #Pathology #Microscopy ... #Dermatology #Clinical
Dermatological semiology of Cutaneous Vasculitis 

Clinicopathologic correlations
 • Purpura, papules, pustules, necrosis: involvement of small vessels
Connective tissue disease ... EGPA • Solid cancers ... Vasculitis #dermpath #dermatology ... lesions #diagnosis #clinical ... manifestations #pathology