45 results
Non-HCV infectious mixed cryoglobulinemia vasculitis - Diagnosis, causes and management - French Vasculitis Study Group

< 5%
vasculitis - Diagnosis ... manifestations - Skin ... with refractory disease ... #Vasculitis #Rheumatology ... #Diagnosis #Management
Renal involvement in 35% of mixed cryoglobulinemia vasculitis 
Associated with : 
 • Absence of skin
vasculitis Associated ... • Absence of skin ... min/1.73 m2 at diagnosis ... • Dialysis at diagnosis ... #Rheumatology #
Dermatological semiology of Cutaneous Vasculitis 

Clinicopathologic correlations
 • Purpura, papules, pustules, necrosis: involvement of small vessels
Connective tissue disease ... EGPA • Solid cancers ... hemopathies (4%) • Cryoglobulinemia ... signs #lesions #diagnosis ... manifestations #pathology
Vasculitis Involving the Skin - Differential Diagnosis Framework

Primary: 50% Cutaneous Vasculitis: Leukocytoclastic Vasculitis
Secondary: CTD: SLE, RA
Diagnosis Framework ... Urticarial/LCV) - Cryoglobulinemic ... : • Behcet Disease ... #skin #dermatology ... differential #diagnosis
Small Vessel Vasculitides
 • Granulomatosis with polyangiitis - Granulomatous manifestations (e.g., nasal crusting, destructive sinusitis, pulmonary
Small Vessel Vasculitides ... Interstitial lung disease ... involvement • Cryoglobulinemic ... in absence of skin ... #diagnosis
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
- Purpura - Skin ... • Autoimmune diseases ... reticularis & skin ... Labs/Diagnosis: ... Cryoglobulins #diagnosis
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
Differential Diagnosis ... purpura • Mixed cryoglobulinemia ... Polyangiitis #GPA #dermatology ... #rash #diagnosis ... #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
- Differential Diagnosis ... ANCA +MPO) • Cryoglobulinemic ... Vasculitis - Skin ... Low levels mixed cryoglobulinemia ... #rheumatology #
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Differential Diagnosis ... purple, hemorrhagic skin ... /HSP • Cryoglobulinemia ... #Differential #Diagnosis ... #hematology #rheumatology
Pulmonary Renal Syndromes and Mimics - Differential Diagnosis Framework
Diffuse alveolar hemorrhage + rapidly progressive glomerulonephritis
90%:
 -
- Differential Diagnosis ... - Anti-GBM Disease ... Complement Levels: SLE, Cryoglobulinemic ... multiorgan failure - Cancer ... #Differential #Diagnosis