pathology hematology hepatology treatment clinical differential anemia syndrome table smear diagnosis dermatology disorders autoimmune workup common cold

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19 results

Pancytopenia - Workup and Differential Diagnosis Algorithm
Consumption Disorders
1. Autoimmune Mediated Pancytopenia
2. Splenic Sequestration
Peripheral Destruction

Pancytopenia - Workup ... and Differential ... Diagnosis Algorithm ... Acquired Aplastic Anemia ... #Hematology

Acquired von Willebrand Syndrome - Diagnosis and Management
• Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,

von Willebrand Syndrome ... - Diagnosis and ... thrombocythemia), Autoimmune ... #treatment #hematology ... #differential

Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?

Peripheral Smear ... → Refer to hematology ... for workup, including ... hemolysis, deficiency anemia ... #hematology

Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
1. Cold Agglutinins (CAD)
2. Donath-Landsteiner

Agglutinin Syndrome ... symptoms - most common ... anemia • Cold ... IgM) • Blood smear ... #hematology #diagnosis

Hemolysis - Differential Diagnosis Framework

1) Environment
- Fragmentation
- MAHA: TTP, HUS, DIC, HELLP

Membrane): - Autoimmune ... : Warm AIHA, Cold ... Defects: Sickle cell anemia ... Peripheral Blood Smear ... #Diagnosis #hematology

Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
• Mechanical Trauma (Microangiopathic hemolytic anemia):

Diagnostic Framework ... lymphoproliferative disorders ... Extravascular #Causes #differential ... #diagnosis #hematology ... #anemia

Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
- Prior platelet count, family

- Differential ... Diagnosis and Workup ... practices that could ... changes), high MCV anemia ... #Workup #hematology

Causes of Neutropenia - Differential Diagnosis
Neonate:
- Infection - by far the most common cause
-

Diagnosis Neonate ... hypertension and/or drug treatment ... Megaloblastic anemia-rare ... - Autoimmune disorders ... #hematology

Hemolytic Anemia - Differential Diagnosis Algorithm
• Sickle cells - Consider sickle cell disease (diverse genotypes):

Hemolytic Anemia ... Agglutination - Cold ... Consider RBC membrane disorder ... elliptocytosis, autoimmune ... #workup #hematology

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