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Pathologic Red Blood Cell (RBC) Morphologies and Associated Diseases Acanthocyte (spur cell), Basophilic stippling, Bite cell,
Cell (RBC) Morphologies ... and Associated Diseases ... cell, Other RBC ... Howell-Jolly bodies #RBC ... Basis of Disease
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Red Blood Cell (RBC ... Morphology Microcytic RBC ... Bite Cell RBC: G6PD ... Target Cell RBC ... #differential #diagnosis
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
Decreased RBC ... Anemia of Chronic Disease ... Thalassemia • RBC ... Disorder • RBC ... #Algorithm #Causes
General overview of lung diseases. #diagnosis #causes #lung #disease #restrictive #obstructive #pulmonary #respiratory #pearls #ddxof
overview of lung diseases ... #diagnosis #causes ... #lung #disease ... #obstructive #pulmonary
Causes of False Elevation and Reduction in HbA1c == False Elevation == Decreased RBC turnover • Iron, B-12,
Causes of False ... == Decreased RBC ... Glucose Content • RBC ... Reduction == Increase RBC ... End-stage renal disease
Algorithm and Differential Diagnosis of Macroscopic Hematuria Important Historical Elements: - Painless: suggests malignancy - Painful: suggests calculi/infection - Urinalysis:
and Differential Diagnosis ... dysmorphic RBC’s, RBC ... /WBC casts, proteinuria ... intrinsic renal disease ... neck, prostatic) #Diagnosis
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
- Differential Diagnosis ... 2) External (RBC ... , Drugs, Liver Disease ... 3) Internal (RBC ... Electrolytes: Wilson's disease
Causes of Polycythemia (Erythrocytosis) - Differential Diagnosis Algorithm Relative - Normal RBC Mass / Decreased Plasma Volume
Causes of Polycythemia ... Relative - Normal RBC ... Disease • Cyanotic ... Heart Disease ... Disease #Polycythemia
Interstitial Lung Diseases (ILD) Exposure-Related ILD (a.k.a. extrinsic allergic alveolitis): • Hypersensitivity pneumonitis, Farmer's lung, Bird
Interstitial Lung Diseases ... Connective Tissue Disease ... connective tissue disease ... bronchiolitis-interstitial lung disease ... Interstitial #Lung #Diseases
Hematuria - Differential Diagnosis Framework Gross Hematuria: Red/Dark urine • 1ml blood/liter urine can induce color change
Hematuria: 3 or more RBC ... basement membrane disease ... hematuria: - RBC ... - Dysmorphic RBC ... of glomerular disease
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