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diagnosis management differential hemophagocytic hiv hlh infections infectiousdiseases lymphohistiocytosis associated barre behcet cauda caudaequina cerebritis coagulation comparison dementia dic disease
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
CNS Manifestations ... Demyelinating Syndrome ... Disease, PRES Pathophysiology ... autoantibodies that will cause ... #neurology #rheumatology
CNS Infection in HIV / AIDS - Differential Diagnosis Framework Principles of HIV-Associated CNS Opportunistic Infections: •
HIV / AIDS - Differential ... Antimicrobial treatment ... status, and focal neurologic ... Demyelinating disease caused ... differential #diagnosis #AIDS
TRALI vs TACO - Transfusion Reactions TRALI: • Epidemiology: 0.1% of transfused patientsl • Risk factors: Critical
blood donor • Pathophysiology ... without other cause ... : 33% • Treatment ... : No • Treatment ... Transfusion #Reactions #hematology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... high WBC count cause ... organ damage • Treatment ... : • Pathophysiology ... diagnosis #management #hematology
HIV-Associated Neurocognitive Disorder (HAND) Definition: HIV-Associated Neurocognitive disorders categories: • Asymptomatic neurocognitive impairment • Mild neurocognitive impairment • HIV dementia Pathophysiology: HIV frequently
HIV dementia Pathophysiology ... and infects the CNS ... The clinical syndrome ... disorder #dementia #AIDS ... #Neurology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
skin injury) • Neurologic ... basal ganglia, CNS ... meningitis), MCC CNS ... Arthritis, AS Treatment ... signs #symptoms #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... →Activation of CD8 ... Treatment: • ... diagnosis #management #treatment ... #summary #rheumatology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Hypocomplementemia • Can cause ... /aggregate) of CD4 ... Nephrogenic DI Hematologic ... Adenocarcinoma Treatment ... #Rheumatology #
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
protein C and S Pathophysiology ... Thromboembolism (7%) • CNS ... Treat primary cause ... #treatment #management ... #hematology
Guillain-Barre Syndrome - Summary Acute AIDP that presents with rapidly progressive flaccid weakness Epidemiology: • 1-2 cases/100,000 per
Summary Acute AIDP ... Epidemiology: • 1-2 cases ... Guillain-Barre Pathophysiology ... Treatment: • Plasmapheresis ... #neurology
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