20 results
Lupus (SLE): Mucocutaneous Manifestations

 • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
Lupus (SLE): Mucocutaneous ... plugging -> Discoid Rash ... Malar (butterfly) Rash ... Manifestations #pathophysiology ... diagnosis #signs #symptoms
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
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Systemic Lupus Erythematosus ... 69% - Malar rash ... Diagnosis and Lupus ... autoantibodies #signs #symptoms ... #differential #rheumatology
Systemic Lupus Erythematosus (SLE) - Typical Signs/Symptoms
Alopecia, Fever, Malar rash, Photosensitivity, Adenopathies, Lupus pneumonia, Pleurisy, Pancreatitis,
Typical Signs/Symptoms ... , Fever, Malar rash ... , Oral ulcers, Rash ... Erythematosus #SLE #Signs #Symptoms ... #diagnosis #rheumatology
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
Constitutional symptoms ... NPSLE rare, Malar rash ... constitutional symptoms ... Manifestations: Malar rash ... comparison #table #rheumatology
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Features of Systemic Lupus ... Photosensitivity, Butterfly rash ... Thrombocytopenia #Lupus ... erythematosus #signs #symptoms ... #diagnosis #rheumatology
Primary Sjogren’s Syndrome: Pathogenesis and Clinical Findings
• Primary Sjögren's is a solitary process whereas secondary Sjögren's
primary biliary cirrhosis ... RA) or systemic lupus ... (SLE) Signs / Symptoms ... Sjogrens #Syndrome #Pathophysiology ... Diagnosis #Signs #Symptoms
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
evidence of (fatigue, rash ... Photosensitive rash ... Malignancy (e.g. hematologic ... vein thrombosis Hematologic ... : • Symptoms limited
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
context of other symptoms ... , Drug-induced Lupus ... , Drug-Induced Lupus ... Primary Biliary Cirrhosis ... ANA #patterns #rheumatology
Capnocytophaga Canimorsus Skin Rash

40 M presents w/ N, V, severe epigastric pain. SHx: smoker, drinks 18
dog or cat bite. symptoms ... asplenia, alcoholism, cirrhosis ... abrupt onset of symptoms ... #dermatology #clinical ... #photo
Secondary Syphilis Rash
Secondary syphilis is the most contagious of all the stages of this disease, and
Secondary Syphilis Rash ... The signs and symptoms ... ▪ “Rash” (75% ... Diagnosis #Clinical #Photo ... #Dermatology