13 results
Coagulation Cascade and Anticoagulant Sites of Action

- Amy Chung, MD, MSc https://twitter.com/AmyChung

#AntiCoagulation #Cascade #Anticoagulants #Medications #Pharmacology
#Medications #Pharmacology ... #Pathophysiology ... #Mechanisms #DOAC ... #Hematology
Irritable Bowel Syndrome (IBS) in Pregnancy
 - Pathophysiology
 - Pharmacotherapy
 - Nonpharmacological Treatment

Emory Gastroenterology and Hepatology
Irritable Bowel ... in Pregnancy - Pathophysiology ... Nonpharmacological Treatment ... Gastroenterology and Hepatology ... EmoryGastroHep #Irritable #Bowel
(DOAC interactions) Cancer-treatment specific inducers (↑) and inhibitors (↓)
of cytochrome p450 CYP3A4 and P-glycoprotein.

DOACs are substrates
(DOAC interactions ... ) Cancer-treatment ... DOACs are substrates ... Chemotherapy #Oncology #Hematology ... Interactions #Table #Pharmacology
DOAC Reversal
Emergency surgery or urgent procedure
Stop anticoagulant treatment; volume resuscitation and transfusion as needed
Antidotes:
 • Apixaban,
DOAC Reversal Emergency ... anticoagulant treatment ... not available #DOAC ... anticoagulant #hematology ... #management #pharmacology
Irritable Bowel Syndrome (IBS) - Management
Global IBS Symptoms:
  - Limited trial low FODMAP diet
Irritable Bowel ... Management Global IBS Symptoms ... ♀ with severe symptoms ... Gastroenterology and Hepatology ... gastroenterology #treatment
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... Dehydration • Symptoms ... limb ischemia, bowel ... Lysis Syndrome: • Pathophysiology ... diagnosis #management #hematology
Irritable Bowel Syndrome (IBS) - Diagnosis and Management Summary
Diagnosis:
 • Use a positive diagnostic strategy with
Irritable Bowel ... for diagnosis Treatment ... Gastroenterology and Hepatology ... IBS #Irritable #Bowel ... gastroenterology #treatment
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
blood donor • Pathophysiology ... ARDS to explain symptoms ... : 33% • Treatment ... : No • Treatment ... Transfusion #Reactions #hematology
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
pattern of spread, B symptoms ... Responsive to Treatment ... growth, response to treatment ... Classification #pathophysiology ... #Hematology #Diagnosis
Heparin Induced Thrombocytopenia (HIT) - Diagnosis and Management - GrepMed Handbook

Presentation: 
 • Plts ↓50% (nadir
♀, ↑Age, ESRD Pathophysiology ... , Bivalirudin, DOAC ... Diagnosis #Management #Treatment ... #Hematology #HemeOnc