12 results
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Disease, PRES Pathophysiology ... Puncture, EEG Treatment ... Erythematosus #SLE #CNS #neurology ... cerebritis #diagnosis #management ... #treatment
Algorithm for the Treatment of Membranous Lupus Nephritis
Sub-nephrotic-range proteinuria (<3.5g/d, normal serum albumin) and Preserved kidney
Algorithm for the Treatment ... of Membranous Lupus ... to treat extra-renal ... #Membranous #Lupus ... #management #nephrology
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Guillain-Barre Syndrome ... Pathophysiology ... Treatment: • Plasmapheresis ... Syndrome #diagnosis #management ... #treatment #neurology
Management of Lupus Nephritis
Lupus nephritis (LN) in 10 to 40% of SLE
Hallmark = proteinuria 20.5 g/g
Management of Lupus ... Nephritis Lupus ... or 0.5 g/day → renal ... #treatment #management ... #rheumatology #nephrology
Guillain-Barré Syndrome (GBS)
Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness
Epidemiology:
 • Incidence: 1
Guillain-Barré Syndrome ... the underlying pathophysiology ... and cauda equina TREATMENT ... Syndrome #diagnosis #management ... #neurology
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
Framework and Management ... Heat stroke - Metabolic ... Differential #Diagnosis #Management ... #causes #treatment ... #nephrology
Intracranial Hemorrhage (ICH) and Increased Intracranial Pressure (ICP) - Pathophysiology
ICH Management:
1. Manage Blood Pressure
  •
ICH Management ... lidocaine, +/- pre-treatment ... • Increased metabolic ... #neurology #neurosurgery ... #management
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
Immunosuppressive agents, Renal ... Etiology: • Pathophysiology ... Drug toxicity, Metabolic ... Syndrome #diagnosis #management ... #neurology
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
Agents Regulating Renal ... resistance • Metabolic ... irrigation • Management ... Tolvaptan) • Treatment ... Excretion #Diuresis #Nephrology
Methotrexate Renal Toxicity 
Prevention:
 • Alkalinize the urine, keep urine ph >7
 • Start pre-treatment 12
Methotrexate Renal ... fluids till you see metabolic ... #Methotrexate #Renal ... #Toxicity #management ... #treatment #nephrology