54 results
Metformin Associated Lactic Acidosis (MALA) 

Pathophysiology of MALA
 - Metformin interferes with the activity of the
Acidosis (MALA) Pathophysiology ... use in cellular metabolism ... via anaerobic metabolism ... also includes symptoms ... of metabolic acidosis
Allopurinol and its active metabolite inhibit xanthine oxidase, the enzyme that converts hypoxanthine to xanthine and
and its active metabolite ... #pharmacology #overview ... druginformation #nephrology ... #sideeffects #medications
Tranexamic Acid - Indications and Pharmacology
Pharmacokinetics:
 • MOA: Inhibits plasminogen activation to plasmin & inhibits fibrinolysis
Tranexamic Acid - Indications ... and Pharmacology ... angioedema) • Metabolism ... amount of hepatic metabolism ... #Pharmacology #
Complications of CKD
 - Patients with stages 1-3 ([GFR] >30 mL/min) of CKD are generally asymptomatic;
imbalances or endocrine/metabolic ... #Pathophysiology ... #Nephrology #CKD
Serotonin Syndrome Drug Precipitants and Pharmacology
↑ Serotonin Formation: Tryptophan, Oxitriptan
↑ Serotonin Release: Amphetamines, Cocaine, Mirtazapine
↑ Serotonin
Precipitants and Pharmacology ... Lithium ↓ Serotonin Metabolism ... Serotonin #Syndrome #Pharmacology ... #medications #causes
Refeeding Syndrome: Pathogenesis and clinical findings

Patients at Risk of Refeeding Syndrome:
 - Little or no nutritional
• Incr Glucose Metabolism ... Syndrome - Metabolic ... Syndrome #diagnosis #pathophysiology ... #symptoms #signs
Uric Acid Homeostasis
In the liver, purines are metabolized to uric acid. The last step in purine
step in purine metabolism ... Homeostasis #Gout #Pathophysiology ... #Pharmacology # ... Medications #Management
TiTrATE schema to approach to Dizziness
 • Time Course: Continuous or Episodic
 • Triggers: Present or
yet imprecise symptom ... (psychiatric, metabolic ... differential #diagnosis #neurology
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Pregnancy (AFLP) Pathophysiology ... free fatty acid metabolism ... Intermediate fatty acid metabolism ... postpartum): • Initial symptoms ... diagnosis #management #pathophysiology
Medications Used in Congestive Heart Failure

In CHF, the heart is failing as a pump; cardiac output
Medications Used ... insuffcient to meet the metabolic ... #Pharmacology #CHF ... #Medications #Action