71 results
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
alkalosis • Normal or low ... ratio 0.5%) Differential ... Rhabdomyolysis Treatment ... Syndrome #diagnosis #nephrology ... #management #pathophysiology
Hypokalemia - Differential Diagnosis Algorithm

Transcellular Shift:
 • Alkalosis
 • ↑ beta-2 adrenergic simulation 
 • Erythropoiesis
Hypokalemia - Differential ... vomiting) • Low ... #Differential # ... Diagnosis #Algorithm #nephrology ... #low #potassium
Hypokalemia - Differential Diagnosis Algorithm
Extra-renal Losses:
 • Normal Acid-Base: Low intake
 • Metabolic acidosis: Gl tract
Hypokalemia - Differential ... intake • Metabolic ... Renal Losses: • Metabolic ... #Differential # ... #nephrology
Causes of HyperKalemia - Differential Diagnosis
Increased extracellular K+:
 • Tissue injury
 • Hemolysis
 • Rhabdomyolysis
 •
Causes of HyperKalemia ... - Differential ... lysis syndrome • Metabolic ... blockers - MCW Nephrology ... #Differential #
Causes of Hypokalemia - Differential Diagnosis Algorithm
Increased Loss 
 - Increased GI Loss
 - Increased Urinary
Causes of Hypokalemia ... - Differential ... #Differential # ... causes #potassium #low ... #pathophysiology
Causes of Hypokalemia - Differential Diagnosis Algorithm
Once pseudohypokalemia is ruled out, causes of hypokalemia can be
Causes of Hypokalemia ... - Differential ... filling of bucket (low ... #Differential # ... Causes #workup #nephrology
Hypokalemia Evaluation Algorithm

Before evaluating hypokalemia, life threatening complications such as arrhythmias and paralysis should be looked
consumption • Low ... Pressure: - Metabolic ... diagnosis #Algorithm #differential ... #potassium #nephrology ... #low
Hypokalemia Differential Diagnosis Algorithm
Hypertensive:
 • High Al, Low R - Primary aldosteronism
 • High Al, High
Hypokalemia Differential ... Hypertensive: • High Al, Low ... Gitelman's syndrome #Hypokalemia ... #Differential # ... Diagnosis #Algorithm #nephrology
Algorithm for patients with hypokalemia on the basis of the potassium-to-creatinine ratio in the urine
Urine K+
patients with hypokalemia ... • Cell shift: Hypokalemic ... syndrome #hypokalemia ... urine #potassium #differential ... algorithm #diagnosis #nephrology
Hypokalemia Differential Algorithm
Acidosis
 - RTA
 - Diarrhea
pH Normal 
 1. Decreased Mg 
 2. Intracellular Shift
Hypokalemia Differential ... Metabolic alkalosis ... NephTwitter) #Hypokalemia ... #Differential # ... Causes #Workup #Nephrology