40 results
High Anion Gap Metabolic Acidosis (HAGMA) - Differential Diagnosis - GOLDMARK

Glycols - ethylene and propylene glycol
Oxoproline
High Anion Gap Metabolic ... - Differential Diagnosis ... underexcretion of acids ... #Differential #Diagnosis ... GOLDMARK #mnemonic #nephrology
Metformin Associated Lactic Acidosis (MALA) 

Pathophysiology of MALA
 - Metformin interferes with the activity of the
Acidosis (MALA) Pathophysiology ... use in cellular metabolism ... Diagnosis of MALA ... LacticAcidosis #Toxicity #Toxicology ... #Diagnosis #Management
Colchicine Toxicity 
Naturally-occurring plant alkaloid [Autumn Crocus and Glory Lilly]
2-24 hrs 
 • Severe GI distress
Renal failure • Metabolic ... acidosis • ARDS ... Colchicine #Toxicity #Toxicology ... Symptoms #Signs #Diagnosis
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
blood donor • Pathophysiology ... : 33% • Treatment ... transfusion • Pathophysiology ... : No • Treatment ... Reactions #hematology #diagnosis
Salicylate Toxicity - Diagnosis and Management

Consider if:
1) Patient is hot and altered
2) You see tachypnea with
Salicylate Toxicity - Diagnosis ... show anion-gap metabolic ... Labs: Anion-Gap Metabolic ... Aspirin #Toxicity #Toxicology ... #Treatment
Clozapine Toxicology
Clozapine is an atypical antipsychotic most often reserved for use in patients who have treatment-resistant
Clozapine Toxicology ... patients who have treatment-resistant ... - Metabolism - ... #Clozapine #Toxicology ... #Toxicity #Diagnosis
Gitelman Syndrome Pathophysiology
Gitelman Syndrome is a rare autosomal recessive salt-losing tubulopathy with a prevalence of 1-
Gitelman Syndrome Pathophysiology ... → Hypokalemia Metabolic ... Gitelman #Syndrome #Pathophysiology ... #nephrology #diagnosis
 Acute Iron Poisoning

There are five classically described phases of toxicity:
Gastrointestinal phase (~6 hours post-ingestion)
 -
deterioration Shock and metabolic ... - Anion gap metabolic ... multi-organ failure (ARDS ... Poisoning #Toxicity #Toxicology ... #Diagnosis #Management
Imaging Patterns of Toxic and Metabolic Brain Disorders

Thalami, Mammillary Bodies and Tectum: Wernicke Encephalopathy
Dentate Nuclei: Metronidazole,
Patterns of Toxic and Metabolic ... MRI #Patterns #Toxicology ... #Metabolic #Brain ... #Differential #Diagnosis ... #Radiology #Neurology
Vancomycin Associated Acute Kidney Injury

 • Drug induced acute kidney injury is generally defined as a
Treatment includes ... #pharmacology #toxicology ... #diagnosis #management ... #nephrology