26 results
Metformin Associated Lactic Acidosis (MALA) 

Pathophysiology of MALA
 - Metformin interferes with the activity of the
Acidosis (MALA) Pathophysiology ... use in cellular metabolism ... via anaerobic metabolism ... presentation - Clinical ... LacticAcidosis #Toxicity #Toxicology
Complications of CKD
 - Patients with stages 1-3 ([GFR] >30 mL/min) of CKD are generally asymptomatic;
imbalances or endocrine/metabolic ... derangements are not clinically ... disturbances manifest clinically ... #Pathophysiology ... #Nephrology #CKD
Imaging Patterns of Toxic and Metabolic Brain Disorders

Thalami, Mammillary Bodies and Tectum: Wernicke Encephalopathy
Dentate Nuclei: Metronidazole,
Patterns of Toxic and Metabolic ... MRI #Patterns #Toxicology ... #Metabolic #Brain ... #Disorders #Clinical ... Diagnosis #Radiology #Neurology
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
Risk factors: Critical ... blood donor • Pathophysiology ... : 33% • Treatment ... transfusion • Pathophysiology ... : No • Treatment
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
may precede the neurologic ... Etiology: • Pathophysiology ... Drug toxicity, Metabolic ... epilepticus Treatment ... underlying cause • Treatment
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Summary Acute AIDP ... Guillain-Barre Pathophysiology ... meningococcal, H1N1) Clinical ... Guillain-Barre Clinical ... #neurology
Intracranial Hemorrhage (ICH) and Increased Intracranial Pressure (ICP) - Pathophysiology
ICH Management:
1. Manage Blood Pressure
  •
Pressure (ICP) - Pathophysiology ... lidocaine, +/- pre-treatment ... • Increased metabolic ... Pressure #ICP #Pathophysiology ... #neurology #neurosurgery
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE) Clinical ... Disease, PRES Pathophysiology ... Puncture, EEG Treatment ... Erythematosus #SLE #CNS #neurology ... diagnosis #management #treatment
Salicylate Toxicity - Diagnosis and Management

Clinical Findings
Pathophysiology
Workup
Treatment

By Stacy Marshall, MD

#Salicylate #Toxicity #Diagnosis #Management #Toxicology #Aspirin #Treatment
Management Clinical ... Findings Pathophysiology ... Workup Treatment ... Diagnosis #Management #Toxicology ... #Aspirin #Treatment
Pisa Syndrome (pleurothotonus) on Physical Exam
A tonic flexion of the trunk of the body to one
Pathophysiology: ... Treatment: anticholinergics ... #PhysicalExam #clinical ... #neurology #posture