45 results
Topical drug formulations, comparison and considerations

#pharmacology #table #medications #comparison #drugs #treatment #pharmacotherapy #dermatology
Topical drug formulations ... , comparison and ... considerations #pharmacology ... #drugs #treatment ... pharmacotherapy #dermatology
Causes of Thrombocytopenia - Differential Diagnosis Algorithm
 
Decreased Megakaryopoiesis
 • Aplastic Anemia
 • Toxic Damage (e.g.
methotrexate) • Drugs ... Alloimmune • anti-HLA antibodies ... Drugs • Quinidine ... HUS • DIC • Vasculitis ... Algorithm #Causes #Hematology
ANCA Vasculitis - GPA, MPA, Eosinophilic GPA

doi:10.1038/s41572-020-0204-y

#ANCA #Vasculitis #GPA #MPA #Eosinophilic #rheumatology #diagnosis #comparison #table
ANCA Vasculitis ... 0204-y #ANCA #Vasculitis ... #Eosinophilic #rheumatology ... #diagnosis #comparison
Pathophysiology of Hypocomplementemic Urticarial Vasculitis

C1q/anti-C1q antibiody ->
Immune Complex Formation - Complement Pathway Activation (C3a and C5a)
Pathophysiology ... Hypocomplementemic Urticarial Vasculitis ... Formation -> Vasculitis ... #HUV #Pathophysiology ... #Rheumatology
Vasculitis Involving the Skin - Differential Diagnosis Framework

Primary: 50% Cutaneous Vasculitis: Leukocytoclastic Vasculitis
Secondary: CTD: SLE, RA
Vasculitis Involving ... 50% Cutaneous Vasculitis ... , infections, drug ... #skin #dermatology ... #rheumatology #
Coagulation Cascade and Anticoagulant Sites of Action

- Amy Chung, MD, MSc https://twitter.com/AmyChung

#AntiCoagulation #Cascade #Anticoagulants #Medications #Pharmacology
#Medications #Pharmacology ... #Pathophysiology ... Mechanisms #DOAC #Hematology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Secondary Causes: - Drug ... • Ig A vasculitis ... spotted fever • Drug ... Differential #Diagnosis #hematology ... #rheumatology #
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
three primary pathophysiologic ... Purpura Anti-GBM antibodies ... Glomerulonephritis #Vasculitis ... diagnosis #algorithm #rheumatology
Autoantibodies and their Disease Associations
ANA - Non-specific; common in SLE, autoimmune hepatitis
Anti-CCP, Rheumatoid factor - RA
Anti-dsDNA
Anti-histone - Drug-induced ... disease c-ANCA - Vasculitis ... granulomatosis p-ANCA - Vasculitis ... diagnosis #table #rheumatology ... #antibodies
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies)
 • Systemic lupus erythematosus
   1. Anti-dsDNA
Antineutrophil cytoplasmic antibodies ... Anti-histone (in drug-induced ... ANCA-Associated Vasculitis ... Renal-limited vasculitis ... #diagnosis #rheumatology