10 results
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Disorders Testing Algorithm ... evaluation or workup ... glucocorticoid treatment ... organ-specific signs ... #Differential #
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis
Baseline Investigations: full blood count with differential,
Acute Kidney Injury ... - AKI Workup Algorithm ... clinical context and signs ... #Injury #AKI #Workup ... #Algorithm #Differential
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... Dehydration • Symptoms ... - ACS, AKI, acute ... WBC >100k, + lab signs ... : • Pathophysiology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
Platelet Count - Differential ... Diagnosis Algorithm ... hematology for workup ... Rebound effect from treatment ... Kawasaki, Nephrotic syndrome
Approach to Headaches - Differential Diagnosis Algorithm

Red flags (PHANTOMS):
 • Pattern change, progressively worse, papilledema
 •
to Headaches - Differential ... Diagnosis Algorithm ... papilledema • Horner syndrome ... ) • Systemic symptoms ... arteritis • Acute
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Diagnosis Algorithm ... pattern of spread, B symptoms ... Treated Like Acute ... Classification #pathophysiology ... #algorithm
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... Pathophysiology ... Diagnosis: >3 symptoms ... initiation • Differential
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
Etiology: • Pathophysiology ... Neurological symptoms ... : Acute onset 2 ... Reversible course Differential ... , ADEM, Acute toxic
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
with no early symptoms ... Physical Exam/Signs ... microglobulin Treatment ... ’s lymphoma or acute ... Leukemia #diagnosis #workup
It is important to recognize Acute Decompensated Heart Failure (ADHF) as more than just simply a
important to recognize Acute ... coronary syndrome ... #diagnosis #differential ... #algorithm #management ... icu #clinical #pharmacology