33 results
Blood Disorders - Markers and Differential Diagnosis Algorithm 
Acute
 • Myloid (AML) - CD13, CD33, CD34,
Blood Disorders ... - CD7, CD3 Chronic ... Pelger-Huet, Macrocytic anemia ... bcr-able (+) ↑ WBC ... #Disorders #hematology
Red Blood Cell (RBC) Morphology
Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Red Blood Cell ( ... disease, McLeod blood ... Unstable hemoglobin disorders ... differential #diagnosis #hematology ... #microscopy #atlas
Anemia - Underproduction Diagnostic Algorithm
 - Iron deficiency anemia
 - Anemia of chronic inflammation
 - Anemia
Diagnostic Algorithm ... - Anemia of chronic ... Probable bone marrow disorder ... #hematology #diagnosis ... #differential #workup
Overall Approach to Anemia - Differential Diagnosis Algorithm

Blood Loss
 • Acute Bleed - Normocytic / Normochromic
Blood Loss ... RBCs on Smear • Chronic ... • Anemia of Chronic ... Membrane Disorder ... #Causes #Hematology
Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
 • Artifact (redo CBC)
Autonomous:
 • Essential thrombocytosis
 • Polycythemia
Artifact (redo CBC ... : • Acute or Chronic ... • Rheumatic disorders ... Iron deficiency anemia ... #Causes #Hematology
Anemia Diagnostic Algorithm

Mean corpuscular (cell) volume (MCV): Average RBC size. Under 80 = microcytic. Between 80-95
Anemia Diagnostic ... in peripheral blood ... High in acute blood ... (BM) ablative disorders ... #Workup #Hematology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
the peripheral blood ... count ↑ PLT • ↑ PBS ... - infiltrates (anemia ... -> Invade Skin: ... #Leukemia #Hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
→ Refer to hematology ... for workup, including ... : Acute blood loss ... • Infections: Chronic ... #hematology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Hepatomegaly • Skin ... lymphoproliferative disorders ... Lymphocytosis: Absolute blood ... • Neutropenia, anemia ... #oncology #hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Diagnosis and Workup ... plateletcount), peripheral blood ... changes), high MCV anemia ... not required in all ... #hematology