26 results
Babesia spp. on Peripheral Blood Smear Microscopy
 - Multiple small parasites per RBC
 - "maltese cross"
Babesia spp. on Peripheral ... Blood Smear Microscopy ... parasites per RBC ... richdavisphd #Babesia #clinical ... #microscopy #microbiology
Pulmonary Renal Syndrome

Definition: Diffuse alveolar hemorrhage + Glomerulonephritis
Presentation (Pulmonary and renal manifestations can occur weeks apart):
Hematuria, Hemoptysis, Peripheral ... ANCA-positive vasculitis ... polyangiitis, Microscopic ... ANCA-negative vasculitis ... Investigations • Labs: CBC
Autoantibodies and their Disease Associations
ANA - Non-specific; common in SLE, autoimmune hepatitis
Anti-CCP, Rheumatoid factor - RA
Anti-dsDNA
biliary cirrhosis (PBC ... disease c-ANCA - Vasculitis ... granulomatosis p-ANCA - Vasculitis ... Microscopic polyangiitis ... diagnosis #table #rheumatology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
Differential Diagnosis Algorithm ... Peripheral Smear ... Rheumatologic, Vasculitides ... Kawasaki, Nephrotic syndrome ... Differential #Diagnosis #Algorithm
VEXAS (Vacuoles, E1 enzyme, X-linked, Autoinflammatory, Somatic) Syndrome
Clinical Syndrome:
 • Common Clinical Features: alveolitis, ear and
Clinical Syndrome ... : • Common Clinical ... recurrent fevers, vasculitis ... • Hematologic ... cells including peripheral
Diagnosis of Cryoglobulinemia Vasculitis

1) Presence of cryoglobulin 
Circulating immunoglobulins that precipitate with cold temperature and dissolve
Cryoglobulinemia Vasculitis ... not related to clinical ... Hyperviscosity syndrome ... purpura +++ • Peripheral ... #Diagnosis #Rheumatology
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Glomerulonephritis - Peripheral ... : • Clinical triad ... skin necrosis, peripheral ... - GPA, EGPA, microscopic ... classification #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
PR3-ANCA): • Microscopic ... glomeruli, and peripheral ... • Cogan Syndrome ... Lab Tests: • CBC ... Dx: GPA, EGPA, microscopic
ANCA-Associated Vasculitis
There are many definitions, but most come down to the presence of granulomas (pathologically or
ANCA-Associated Vasculitis ... pathologically or clinically ... inflammation: • Microscopic ... differential #diagnosis #algorithm ... #rheumatology
Plasmodium Falciparum Blood Smear.
Key features suggesting Plasmodium falciparum:
- extreme parasitemia
- normocytic RBCs (vivax, ovale prefer big
multiples per RBC ... #peripheral #clinical ... #microscopy #microbiology