33 results
Systemic Sclerosis (Scleroderma)
Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs
3
skin thickening Signs ... and Symptoms: ... (interstitial lung ... #rheumatology #diagnosis ... #signs #symptoms
Clinical manifestations of acute liver failure 

Brain: 
Hepatic encephalopathy,  
Cerebral edema,  
Intracranial hypertension,
: Systemic inflammatory ... pancreatitis Lungs ... : Acute lung injury ... liver #failure #Signs ... #Symptoms #Diagnosis
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations

 • Immune Complex Deposition
    - Arthralgia, Arthritis
Systemic Lupus Erythematosus ... Osteoporosis #Systemic ... Erythematosus #SLE #MSK ... pathophysiology #signs ... #symptoms #diagnosis
Multiple Sclerosis - Summary

Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
Examination: • UMN signs ... Clonus, Babinski’s sign ... • Lhermitte’s sign ... pupillary defect SIGNS ... Signs and symptoms
Pemphigus Vulgaris vs Bullous Pemphigoid - Comparison Table
Pemphigus Vulgaris
 • Epidemiology: Average age 40-60
 • Time
, relapsing • Symptoms ... ruptured • Nikolsky sign ... Tense • Nikolsky sign ... : Systemic or topical ... Pemphigoid #Comparison #diagnosis
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Clinical Features of Systemic ... effusion, Restrictive lung ... joints Nervous system ... erythematosus #signs ... #symptoms #diagnosis
Autoimmune Myositis
Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
weakness, less systemic ... symptoms, and less ... heliotrope rash, Shaw sign ... , holster sign, ... after 2 years of treatment
Achilles Tendon Rupture - Pathogenesis and clinical findings
 • The Achilles tendon is 15cm long in
tendon is 15cm long ... pre-determined etiology Signs ... TendonRupture #diagnosis ... #signs #symptoms ... pathophysiology #msk
Heart failure with Reduced Ejection Fraction (HFrEF)
Clinical Presentation
1. Typical symptoms: dyspnea, orthopnea paroxysmal noctumal dyspnea, fatigue,
Typical symptoms ... More Specific Signs ... Less Specific Signs ... Chest x-ray: signs ... acute HF → no signs
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
 -
Systemic Lupus Erythematosus ... Myositis 4% - Lung ... Lupusreference #SLE #Systemic ... autoantibodies #signs ... #symptoms #mimickers