30 results
Jaw Clonus on Physical Exam

A 24-year-old man presented with progressive dysphagia, dysarthria, and weakness in his
clonus and muscle fasciculations ... consistent with a diagnosis ... #Jaw #Clonus #PhysicalExam ... Clinical #Video #ALS ... #Neurology #NEJM
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... (for secondary APS ... Erythematosus #SLE #CNS #neurology ... #rheumatology # ... #management #treatment
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
Muscle twitching (fasciculations ... BULBAR: Tongue fasciculations ... Other possible diagnosis ... Lateral #Sclerosis #neurology ... #diagnosis #management
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
vs Tumor Lysis Syndrome ... hyperviscosity syndrome ... #Tumor #Lysis #Syndrome ... #TLS #diagnosis ... #management #hematology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
skin injury) • Neurologic ... Medium and large also ... ) Differential Diagnosis ... #diagnosis #management ... signs #symptoms #rheumatology
Horner's Syndrome on Physical Exam

A 75yoF was referred in for facial swelling and eyelid changes 1
Horner's Syndrome ... consistent with a diagnosis ... of Horner's syndrome ... ophthalmology #physicalexam ... #neurology #Anisocoria
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis

Neurologic-Centered:
 (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
- Differential Diagnosis ... Neurologic-Centered ... Features: POEMS, AL ... capillary leak syndrome ... #hematology #oncology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... unless severe APLS ... coagulopathy, RRT/IMV as ... Differentiation #Syndrome ... #management #hematology
Lower Extremity Dermatomes and Myotomes
Reflexes: 
 • Knee - L2, L3, L4
 • Ankle - S1
• Cauda Equina Syndrome ... fibular neck such as ... Dermatomes #Myotomes #diagnosis ... #neurology #sensory ... #motor #leg #physicalexam
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
may precede the neurologic ... factor PRES Diagnosis ... edema visualized as ... #diagnosis #management ... #neurology