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diagnosis sle erythematosus neurology systemic druginduced hematology summary thrombocytopenia activation anticoagulation antiphospholipid aps barre behcet cerebritis cns comparison dermatology disease
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
: -10% of all lupus ... to 1:1 F:M • Clinical ... 40, F:M 9:1 • Clinical ... comparison #table #rheumatology ... #diagnosis #management
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... 40, F:M 9:1 • Clinical ... of SLE versus DIL ... life-threatening • Treatment ... #Summary #rheumatology
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
Systemic Lupus Erythematosus ... Initial screening test ... severe disease Treatment ... Summary #diagnosis #rheumatology ... #management
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
SJIA], systemic lupus ... Liver function tests ... Treatment: • Corticosteroids ... #Diagnosis #Management ... #Hematology #Rheumatology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE) Clinical ... Demyelinating Syndrome ... CNS #neurology #rheumatology ... cerebritis #diagnosis #management ... #treatment
Drug Induced Lupus (DIL) • Epidemiology: -10% of all lupus cases, drug-dependent, 4:1 to 1:1 F:M
: -10% of all lupus ... to 1:1 F:M • Clinical ... #DIL #rheumatology ... #diagnosis #treatment ... #management
Antiphospholipid Syndrome (APS) APS is a rare autoimmune disorder characterized by recurring blood clots resulting from antibodies
Antiphospholipid Syndrome ... ): • Lupus anticoagulant ... Anticardiolipin antibodies (aCL ... to be present Treatment ... APS #diagnosis #management
Posterior Reversible Encephalopathy Syndrome (PRES) Overview Clinico-Radiological Syndrome, characterized by: • Headache • Seizures • Altered mental
circulation: MCA ACA ... level (mean 58 mg/dL ... epilepticus Treatment ... underlying cause • Treatment ... #diagnosis #management
REBEL Review 99: Serotonin Syndrome via Yosuf Alam, MSIV Presentation: Altered mentd status, Seizures, Myoclonus, Hypertension, Hyperthermia
99: Serotonin Syndrome ... Diagnosis: Clinical ... confirmatory lab tests ... Cornerstone of treatment ... SerotoninSyndrome #management
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
association • M > F Clinical ... (Clinical Dx). ... Arthritis, AS Treatment ... #diagnosis #management ... signs #symptoms #rheumatology
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