100 results
Immune Reactions and Immunosuppressant Drugs

Glucocorticoids - Inhibition of cytokine synthesis, e.g., IL-1, IL-2
Muromonab-CD3 - Monoclonal antibody
Calcineurin
., IL-1, IL-2 Muromonab-CD3 ... Basiliximab - IL ... Suppression of IL ... Immunosuppressant #Drugs #Pharmacology ... #Pathophysiology
Contraception Quick Start Algorithm
 1. Pill, Patch, Ring, Injection
 2. Progestin IUD or Implant
 3. Copper
Start Algorithm 1. ... , Patch, Ring, Injection ... Progestin IUD or ... Algorithm #gynecology #management ... #IUD #birthcontrol
Adjuvant therapies in critical care: steroids to treat infectious diseases
 - Severe Community Acquired Pneumonia
steroids to treat infectious ... jirovecii pneumonia, id ... InfectiousDiseases #Infections ... #Pharmacology # ... Management #Treatment
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... Triggering factor (infection ... cytokines (TNFa,lL1, IL6 ... Lymphohistiocytosis #diagnosis #management ... treatment #summary #rheumatology
Mild Acne Treatment - Comedones (black/whiteheads), +/- few pustules 
1. Benzoyl Peroxide (BP) 
2. Topical Retinoid
Mild Acne Treatment ... few pustules 1. ... First line pharmacologic ... #Management #Comedones ... #Pharmacology #
Diagnosis and Management of Hypocomplementemic Urticarial Vasculitis (HUV)

Diagnosis of HUV
1) Chronic urticaria 
2) Leukocytoclastic vasculitis 
3)
Diagnosis and Management ... Diagnosis of HUV 1) ... anti-IgE, anti-IL ... -1 Dr. ... #Rheumatology
Anti-C. Difficile - Antibiotics Class Overview
 1. Metronidazole – (see anti-anaerobe section above for more details).
Class Overview 1. ... second episode of mild-moderate ... C.difficile infection ... severe C.diff infection ... Fidaxomicin (PO) #Pharmacology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Diagnosis and Management ... diagnosis: 70 years old ... risk-stratification • Risks: infection ... acute leukemia Management ... #treatment #hematology
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
• Affects 1:25,000 ... and 1:50,000 patients ... and M panel Management ... hypogammaglobulinemia #immunology #hematology ... #diagnosis #management
Anti-IL6 Agents (Tocilizumab, Siltuximab) in COVID19

IL-6 activates T cells and macrophages, among other cell types (see
Anti-IL6 Agents ... in COVID19 IL ... respiratory tract infection ... Siltuximab #COVID19 #Pharmacology ... #Management #Medications