42 results
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Syndrome (MD) - Diagnosis ... : 70 years old, ... only curative treatment ... #Management #treatment ... #hematology #oncology
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
blood donor • Pathophysiology ... : 33% • Treatment ... transfusion • Pathophysiology ... : No • Treatment ... #diagnosis #comparison
Who to test for BRCA 1/2?
Female Breast Cancer:
 • ≤ 45-50 years at diagnosis
 • Triple
test for BRCA 1/ ... 45-50 years at diagnosis ... relative meeting criteria ... #indications #oncology ... Cancer #screening #diagnosis
Adult Onset Still's Disease
Systemic inflammation with urticarial rash.
Rash: 
 • Nonpruritic, evanescent (correlates with time of
- Yamaguchi criteria ... should be major: 1. ... Treatment - Mild ... : NSAIDS Treatment ... #rheumatology #
Polycythemia Vera (PV) - Diagnosis and Management Summary
Diagnostic Criteria:
 • Elevated hemoglobin and/or hematocrit AND
 •
Polycythemia Vera (PV) - Diagnosis ... Management Summary Diagnostic ... Criteria: • Elevated ... erythropoietin 1/ ... #hematology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Triggers: ATRA treatment ... Pathophysiology ... symptoms, or> 1 ... Renal Failure Treatment ... #oncology
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
minimal tumor burden Diagnosis ... Manifestations: 1) ... Lymphocytic #Leukemia #oncology ... #hematology #hemeonc ... #diagnosis #management
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
-1 and IL-6, leading ... Histopathologic criteria ... Treatment: • Corticosteroids ... Activation #Syndrome #Diagnosis ... #Rheumatology
Kawasaki Disease (KD) - Diagnosis and Management Summary

Kawasaki Disease (KD) is the most common vasculitis of
Disease (KD) - Diagnosis ... Criteria - Fever ... following: 1. ... KD #vasculitis #rheumatology ... #management #treatment
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... cytokines (TNFa,lL1, IL6 ... Unknown cause Treatment ... #management #treatment ... #summary #rheumatology