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diagnosis management hemophagocytic lymphohistiocytosis psychiatry signs symptoms cppd disease activation adhd adult aosd attentiondeficithyperactivedisorder calcium cd classification comparison conduct deposition
Hemophagocytic Lymphohistiocytosis (HLH) Clinical Features: Fever, Splenomegaly, Hepatomegaly, Lymphadenopathy, Confusion Classic lab findings in HLH: ↑↑ ferritin, Anemia,
activity, ↑ soluble IL ... Society Criteria ... activity • ↑ soluble IL ... Lymphohistiocytosis #diagnosis #hematology ... #criteria
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
-1 and IL-6, leading ... hypersensitivity syndromes • HLH ... Histopathologic criteria ... Diagnosis #Management #Hematology ... #Rheumatology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH ... ) Pathophysiology ... cytokines (TNFa,lL1, IL6 ... • Familial HLH ... treatment #summary #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH) Diagnostic Criteria - 2004 vs 2009 At least three of the following: -
Lymphohistiocytosis (HLH ... ) Diagnostic Criteria ... CD25 (soluble IL2 ... @PulmCrit #HLH ... #Hematology
Adult Onset Still's Disease Systemic inflammation with urticarial rash. Rash: • Nonpruritic, evanescent (correlates with time of
5 of the below criteria ... should be major: 1. ... Minor criteria include ... Treatment - Mild ... AOSD #diagnosis #rheumatology
Attention Deficit Hyperactive Disorder (ADHD): Pathogenesis and clinical findings - For diagnosis, must have either 26
at > 17 years old ... than females (4:1) ... AttentionDeficitHyperactiveDisorder #ADHD #BehavioralDisorder ... #Pathophysiology ... signs #psychiatry #criteria
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Hodgkin's lymphoma (HL ... B symptoms in 1/ ... rich classical HL ... through Ann Arbor criteria ... classification #hematology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Non-autoimmune rheumatologic ... • Acute lupus pneumonitis ... • ANA titers > 1: ... Ro/La, anti-Jo-1, ... Erythematosus #Diagnosis #Rheumatology
CPPD vs Gout == CPPD == Think About CPPD When: • Self-limited synovitis after surgery/trauma (> 65
trauma (> 65 years old ... disease states Pathophysiology ... arthritic flare. 1. ... to Manifest: 1. ... Gout #Comparison #rheumatology
Conduct Disorder (CD): Pathogenesis and clinical findings - Must have >3 symptoms present in the past
months, with >1 ... , criteria must ... in childhood (> 1 ... #Conduct #CD #BehavioralDisorder ... #Pathophysiology
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