20 results
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
 -
- Anti-PCNA 1- ... (aPL) 30-45% Differential ... autoantibodies #signs #symptoms ... #mimickers #differential ... #rheumatology
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... Constitutional symptoms ... Prognosis: Usually mild ... constitutional symptoms ... comparison #table #rheumatology
Causes of Interstitial Lung Disease - Differential Diagnosis Algorithm
Idiopathic Interstitial Pneumonia
 • (UIP) Usual Interstitial Pneumonia
Lung Disease - Differential ... this should be 1° ... Arthritis, Systemic Lupus ... Chronic Radiation Pneumonitis ... Lung #Diseases #ILD
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
permanent alopecia Differential ... pneumonitis • ... : • Symptoms limited ... • ANA titers > 1: ... Ro/La, anti-Jo-1,
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
-1 and IL-6, leading ... disease • Systemic lupus ... SJIA], systemic lupus ... Histopathologic criteria ... #Rheumatology
Adult Onset Still's Disease
Systemic inflammation with urticarial rash.
Rash: 
 • Nonpruritic, evanescent (correlates with time of
the chest/trunk Symptoms ... 5 of the below criteria ... should be major: 1. ... Minor criteria include ... AOSD #diagnosis #rheumatology
Heat Illnesses and Heat Stroke - Differential Diagnosis Framework

Heat Cramps:
 • Muscle pain or spasm -
Heat Stroke - Differential ... Collapse: • Pathophysiology ... Syncope • Signs/Symptoms ... heat stress • Criteria ... Multi-system illness: 1.
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS)
Definition: 
 • Severe adverse drug reaction, characterized by
Symptoms: • The ... Criteria for Diagnosis ... : 1. ... Resolution > 15 days Differentials ... withdrawal • Mild
Attention Deficit Hyperactive Disorder (ADHD): Pathogenesis and clinical findings
 - For diagnosis, must have either 26
have either 26 symptoms ... at > 17 years old ... than females (4:1) ... BehavioralDisorder #Pathophysiology ... signs #psychiatry #criteria
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
ATRA treatment Pathophysiology ... Diagnosis: >3 symptoms ... , or> 1 with no ... initiation • Differential ... diagnosis #management #hematology