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diagnosis management differential table associations autoantibodies cppd dermatology diseases myositis ana anca antibody antimda5 antimda5dm antineutrophil antinuclear antinxp2 antinxp2dm arterial
Myositis Specific Antibodies (MSAs) Dermatomyositis: MDA5, TIF1y, NXP2, Mi-2, SAE Anti-Synthetase Syndrome: Jo-1, PL7, PL12, EJ, OJ Immune Mediated
Myositis Specific Antibodies ... (MSAs) Dermatomyositis ... Anti-Synthetase Syndrome: Jo-1, ... Myositis #Specific #Antibodies ... clinical #diagnosis #rheumatology
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
Antineutrophil cytoplasmic antibodies ... Polymyositis and dermatomyositis ... 1. ... Antineutrophil #antibodies ... #diagnosis #rheumatology
Dermatomyositis (DM) and Polymyositis (PM): Pathogenesis and clinical findings Elevated Antinuclear Antibodies: Anti-Jo-1, Anti-OJ, Anti-Mi2, Anti-SRP, Anti-EJ,
Dermatomyositis ... Elevated Antinuclear Antibodies ... : Anti-Jo-1, Anti-OJ ... dehydrogenase (LD ... PM #Diagnosis #Pathophysiology
ANTI-MDA5 DERMATOMYOSITIS Cutaneous manifestations: • Periorbital heliotrope (blue-purple) rash with edema • Erythematous rash on the face, or the
the disease and ILD ... increases and ILD ... prevalence of RP-ILD ... Phenotype 1 ... #rheumatology #
Autoantibodies and their Disease Associations ANA - Non-specific; common in SLE, autoimmune hepatitis Anti-CCP, Rheumatoid factor - RA Anti-dsDNA
Drug-induced SLE Anti-Jo-1 ... Polymyositis / Dermatomyositis ... diagnosis #table #rheumatology ... #antibodies
Autoantibodies in Rheumatology • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Autoantibodies in Rheumatology ... others (RNP, aPL antibodies ... Myositis: Anti-JO-1, ... RNA Polymerase Ill ... Autoantibodies #Rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Still disease, dermatomyositis ... • Acute lupus pneumonitis ... • ANA titers > 1: ... Ro/La, anti-Jo-1, ... SCL-70, RNP antibodies
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework VENOUS THROMBOSIS • Acquired Risk Factors: - >48 hours
Ischemic Liver, IBD ... Antiphospholipid antibodies ... Venous #Arterial #pathophysiology ... #hematology #differential
Anti-NXP-2 Dermatomyositis What? DM with generalized subcutaneous edema Pts have more myalgias, more severe weakness, and an increased prevalence
• Antibodies targeting ... : • ILD was diagnosed ... Prednisone at 1 ... methylprednisolone 1 ... diagnosis #management #rheumatology
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
Anti-MDA5 (RP-ILD ... ), dermato-rheumatologic ... Ab • Anti-Jo-1 ... enzymes • Anti-Jo-1 ... Myositis #Myopathy #rheumatology
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