31 results
Connective tissue disease-associated interstitial lung diseases

LIP: lymphoid interstitial pneumonia. NSIP: nonspecific interstitial pneumonia. OP: organizing pneumonia.
interstitial lung diseases ... DM/PM : dermatomyositis ... ConnectiveTissueDiseases #ILD ... Differential #Comparison #Table ... #Pulmonary #Rheumatology
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
infection • Lyme disease ... Seborrhea • Dermatomyositis ... migrans • Lyme disease ... gangrenosum • IBD ... differential #diagnosis #rheumatology
Myositis Specific Antibodies (MSAs)

Dermatomyositis: MDA5, TIF1y, NXP2, Mi-2, SAE
Anti-Synthetase Syndrome: Jo-1, PL7, PL12, EJ, OJ
Immune Mediated
Antibodies (MSAs) Dermatomyositis ... Anti-Synthetase Syndrome: Jo-1, ... clinical #diagnosis #rheumatology ... #table
Autoantibodies and their Disease Associations
ANA - Non-specific; common in SLE, autoimmune hepatitis
Anti-CCP, Rheumatoid factor - RA
Anti-dsDNA
Autoantibodies and their Disease ... Drug-induced SLE Anti-Jo-1 ... Polymyositis / Dermatomyositis ... #diagnosis #table ... #rheumatology #
ANTI-MDA5 DERMATOMYOSITIS

Cutaneous manifestations:
• Periorbital heliotrope (blue-purple) rash with edema
• Erythematous rash on the face, or the
severity of the disease ... and ILD • Liver ... increases and ILD ... Phenotype 1 ... #rheumatology #
On the left some diseases with a nodular pattern.
1. Hypersensitivity pneumonitis: ill defined centrilobular nodules.
2. Miliary
the left some diseases ... nodular pattern. 1. ... Hypersensitivity pneumonitis ... Hypersensitivity pneumonitis ... Differential #Comparison #Table
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies)
 • Systemic lupus erythematosus
   1. Anti-dsDNA
erythematosus 1. ... Polymyositis and dermatomyositis ... 1. ... antibodies #diagnosis #rheumatology ... #diseases
Autoantibodies in Rheumatology
 • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Autoantibodies in Rheumatology ... Myositis: Anti-JO-1, ... RNA Polymerase Ill ... Autoantibodies #Rheumatology ... #associations #table
Cold Urticaria
Prevalence - 0.05% in the population
Disease onset - Mostly 2nd to 4th decades of life
Causes
associations - 1. ... of symptoms - 1- ... cryofibrinogen - < 1% ... Urticaria #diagnosis #rheumatology ... #comparison #table
Summary of Coagulation Deficiencies
Inherited:
 • Hemophilia A - Deficiency of Factor VIII
 • Hemophilia B -
Malabsorption (e.g. celiac disease ... , CF, IBD) • Anticoagulant ... Advanced Liver Disease ... Deficiencies #Summary #table ... comparison #diagnosis #hematology