18 results
Autoantibodies and their Disease Associations
ANA - Non-specific; common in SLE, autoimmune hepatitis
Anti-CCP, Rheumatoid factor - RA
Anti-dsDNA
Drug-induced SLE Anti-Jo-1 ... Polymyositis / Dermatomyositis ... Anticentromere - CREST ... disease Endomyseal antibody ... diagnosis #table #rheumatology
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Seborrhea • Dermatomyositis ... Heliotrope • Dermatomyositis ... gangrenosum • IBD ... Antiphospholipid-antibody ... differential #diagnosis #rheumatology
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies)
 • Systemic lupus erythematosus
   1. Anti-dsDNA
ANA (Antinuclear Antibody ... erythematosus 1. ... Polymyositis and dermatomyositis ... 1. ... antibodies #diagnosis #rheumatology
ANTI-MDA5 DERMATOMYOSITIS

Cutaneous manifestations:
• Periorbital heliotrope (blue-purple) rash with edema
• Erythematous rash on the face, or the
or the anterior chest ... the disease and ILD ... increases and ILD ... Phenotype 1 ... #rheumatology #
Autoantibodies in Rheumatology
 • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Autoantibodies in Rheumatology ... (anti-nuclear antibody ... Antiphospholipid Antibody ... Myositis: Anti-JO-1, ... RNA Polymerase Ill
Flail Chest Breathing on Physical Exam
74 year-old male, fallen over in the garden. Four rib fractures.
Flail Chest Breathing ... Physical Exam 74 year-old ... The video shows ... non-trauma team. 1. ... PhysicalExam #clinical #video
Flail Chest Breathing on Physical Exam
74 year-old male, fallen over in the garden. Four rib fractures.
Flail Chest Breathing ... Physical Exam 74 year-old ... The video shows ... non-trauma team. 1. ... PhysicalExam #clinical #video
Antinuclear Antibody Testing - Nuclear and Cytoplasmic Patterns
Nuclear Patterns:
 • Homogeneous pattern: 
   -
Antinuclear Antibody ... SLE, SjS, CTD-ILD ... phenomenon - EJ, Jo-1, ... #Antinuclear #Antibody ... differential #diagnosis #rheumatology
Anti-NXP-2 Dermatomyositis

What?
DM with generalized subcutaneous edema
Pts have more myalgias, more severe weakness, and an increased prevalence
or the anterior chest ... levels • NXP-2 antibody ... : • ILD was diagnosed ... Prednisone at 1 ... diagnosis #management #rheumatology
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases

• Septic arthritis - Gram stain and culture of
Rheumatology Workup ... CRP level: (1) ... as opposed to 1 ... years with neck, chest ... diagnosis #testing #Rheumatology