12 results
Suggested algorithm for follow-up of monoclonal gammopathy of undetermined significance (MGUS)
Mayo Clinic Risk Stratification Model. CBC,
significance (MGUS ... ) Mayo Clinic Risk ... monoclonal #gammopathy #MGUS ... Followup #algorithm #diagnosis ... #management #hematology
Suggested algorithm for bone marrow biopsy and skeletal imaging in patients with monoclonal gammopathy of undetermined
significance (MGUS ... 1.5 gm/dL) IgM MGUS ... , low-risk MGUS ... Biopsy #algorithm #diagnosis ... #management #hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
: 70 years old, ... and risk-stratification ... • Risks: infection ... transformation to acute ... #hematology #oncology
Monoclonal Gammopathy of Undetermined Significance (MGUS) - Summary Framework

Hematologic disorder characterized by the presence of either
Summary Framework Hematologic ... sub-types based on the hematologic ... isotype (rarely IgD ... #Significance #hematology ... #diagnosis #oncology
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic ... in those with CLD ... Failure #Cirrhosis #Hepatology ... gastroenterology #management ... #diagnosis
Hemophilia - Diagnosis and Management
Diagnosis:
 • Consistent bleeding history (unless screening for disease in family members
and Management ... severity Treatment - Acute ... Chronic Management ... that ↑ bleeding risk ... #hematology
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Acute Fatty Liver ... headache, malaise) → Acute ... ↓Antithrombin Ill ... ) Differential Diagnosis ... Liver #Pregnancy #hepatology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Attempt if high risk ... Presentation: Subacute-Acute ... • Rare: DAH, acute ... , Anaphylaxis, Acute ... #management #hematology
Complications of Monoclonal Gammopathy of Undetermined Significance (MGUS)
Fracture, Osteoporosis
 - Increased osteoclast activity and bone resorption
Significance (MGUS ... mediators, including IL ... thromboprophylaxis in high-risk ... Complications #diagnosis ... #hematology
Autoimmune Hepatitis

Clinical Presentation
 - Highly variable clinical presentation, from subclinical disease to acute liver failure.
 -
subclinical disease to acute ... , AIH diagnosis ... Hepatitis (eg Viral) Management ... Necrosis) If mild ... #Management #Hepatology