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clinical pocus echocardiogram diagnosis hematology cardiology clot causes differential embolism intransit laboratory pulmonary sign abnormal acutepe anticoagulation aptt cardiac clotintransit
ISTH Scoring System for Disseminated Intravascular Coagulation (DIC) Platelet count: • Expected: Low (or normal) • Elevation
Intravascular Coagulation ... platelet aggregation PT ... consumption of coagulation ... using INR use PT ... to form clots,
Coagulation cascade and anticoagulants Satyendra Dhar MD, @DharSaty #coagulation #coumadin #heparin #warfarin #apaxiban #pradaxa #xarelto #DOAC #vWF
Coagulation cascade ... @DharSaty #coagulation ... xarelto #DOAC #vWF #thrombin ... #ptt #pt
Cool echo - RV strain, McConnell sign, and CLOT IN TRANSIT!! BP is normal and pt
McConnell sign, and CLOT ... is normal and pt ... Echocardiogram #A4C ... Pulmonary #Embolism #Thrombus ... #Clots #InTransit
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 The coagulation cascade is shown, separated into different phases with their endogenous and pharmacological inhibitors shown.
The coagulation ... Thrombin, then primes ... #Coagulation #Cascade ... #platelet #thrombin ... #clot #PT #PTT
This 24M presented with acute onset CP/SOB, hypoxia, HR 150s. What's the diagnosis? Treatment options? Hint:
Thrombus in transit ... Pt had extensive ... Echocardiogram #A4C ... PulmonaryEmbolism #Thrombus ... #Clots #InTransit
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 Pericardial Clot on Echocardiogram ST elevation of acute pericarditis was misdiagnosed as STEMI and thrombolysed with SK
Pericardial Clot ... effusion with large clot ... Pericardial #effusion #clot ... #thrombus #Echocardiogram ... clinical #cardiology #a4c
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 Effect of Anticoagulants on Coagulation Tests PT / INR, aPTT, Anti-Xa Activity, Activated Clotting Time, Thrombin Time,
Anticoagulants on Coagulation ... Tests PT / INR, ... Clotting Time, Thrombin
Thromboelastogram Interpretation Reaction Time (R Value): - Time till initiation of fibrin clot - Treatment: FFP, protamine K
initiation of fibrin clot ... achieve 20 mm clot ... assay representing thrombin-platelet ... Degradation of clot ... Thromboelastography #diagnosis #coagulation
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
Intravascular Coagulation ... • Prolonged PT ... • Increased thrombin ... Fibrinogen: ↓ • PT ... significant fibrin clot
Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
Causes of Abnormal PT ... Congenital intrinsic coagulation ... drugs e.g. direct thrombin ... intravascular coagulation ... differential #hematology #coagulation
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