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hematology differential coagulation abnormal aptt clinical pocus prolonged ptt acute anticoagulation apixaban bleeding bruising cascade clot dabigatran dic disseminated echocardiogram
The coagulation cascade is shown, separated into different phases with their endogenous and pharmacological inhibitors shown.
at the site of injury ... Thrombin, then primes ... #clot #PT #PTT ... #diagnosis #models ... anticoagulation #anticoagulant
How to Evaluate an Abnormal APTT Step 1: Is the PT or APTT Artifactually Prolonged? Step 2: Is
Step 1: Is the PT ... Patient Receiving Anticoagulants ... Heparin, or Direct Thrombin ... to identify the cause ... APTT #prolonged #diagnosis
This 24M presented with acute onset CP/SOB, hypoxia, HR 150s. What's the diagnosis? Treatment options? Hint:
What's the diagnosis ... Thrombus in transit ... Pt had extensive ... Echocardiogram #A4C ... #Clots #InTransit
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 Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
- Differential Diagnosis ... discern these causes ... warfarin, direct thrombin ... deficiency • Anticoagulant ... #Differential #Diagnosis
Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
Causes of Abnormal ... heparin - Other anticoagulants ... Pre-analytical cause ... drugs e.g. direct thrombin ... #diagnosis #differential
Causes of Acute Liver Injury - Differential Diagnosis Hepatocellular - Liver Parenchyma • Infectious: Hepatitis C, A,
Causes of Acute ... Liver Injury - Differential ... Diagnosis Hepatocellular ... : Shock Liver, Thrombus ... #algorithm #hepatology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
• Prolonged PT ... • Increased thrombin ... significant fibrin clot ... Reduction of pro/anticoagulants ... #Coagulation #diagnosis
Causes of Post-Partum Hemorrhage - Differential Diagnosis Algorithm Blood Loss: >500mL post vaginal delivery OR >1000 mL
Causes of Post-Partum ... Algorithm Blood ... Retained blood clots ... or percreta) Thrombin ... #Algorithm #Causes
Greater Saphenous Vein Thrombosis on POCUS Pt-leg pain/redness/swelling. Proximal TRV image. Diagnosis: Greater Saphenous Vein Thrombosis without
Thrombosis on POCUS Pt-leg ... Diagnosis: Greater ... Thrombus from SFJ ... or prior hx of clots ... into the CFV and cause
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