11 results
diagnosis differential causes pathophysiology abnormal aptt cascade clinical clots dic disseminated embolism intransit intravascular mcconnells models pocus prolonged sign anticoagulant
ISTH Scoring System for Disseminated Intravascular Coagulation (DIC) Platelet count: • Expected: Low (or normal) • Elevation
Intravascular Coagulation ... platelet aggregation PT ... consumption of coagulation ... using INR use PT ... Scoring #diagnosis #hematology
The coagulation cascade is shown, separated into different phases with their endogenous and pharmacological inhibitors shown.
The coagulation ... at the site of injury ... #Coagulation #Cascade ... #clot #PT #PTT ... diagnosis #models #hematology
Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
Congenital intrinsic coagulation ... drugs e.g. direct thrombin ... intravascular coagulation ... #differential #hematology ... #coagulation
This 24M presented with acute onset CP/SOB, hypoxia, HR 150s. What's the diagnosis? Treatment options? Hint:
Thrombus in transit ... Pt had extensive ... Clinical #POCUS #Echocardiogram ... #A4C #McConnells ... PulmonaryEmbolism #Thrombus
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 Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
Intravascular Coagulation ... • Prolonged PT ... • Increased thrombin ... Fibrinogen: ↓ • PT ... treatment #management #hematology
Differential Diagnosis for a Prolonged PT and aPTT If the PT and the aPTT are both prolonged,
for a Prolonged PT ... and aPTT If the PT ... drugs (e.g. direct thrombin ... #differential #hematology ... #coagulation
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework VENOUS THROMBOSIS • Acquired Risk Factors: - >48 hours
- Aortic mural thrombus ... Left ventricular thrombus ... intravascular coagulation ... Vasculitis • Injury ... pathophysiology #hematology
Cool echo - RV strain, McConnell sign, and CLOT IN TRANSIT!! BP is normal and pt
is normal and pt ... Clinical #POCUS #Echocardiogram ... #A4C #McConnells ... Pulmonary #Embolism #Thrombus
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 Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
inhibitor of a coagulation ... == NORMAL PT ... intravascular coagulation ... warfarin, direct thrombin ... Differential #Diagnosis #Hematology
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
ALF): • Liver injury ... hepatocellular injury ... • Albumin • Coagulation ... factors: PT/INR ... #differential #Hepatology
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