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diagnosis coagulation abnormal aptt causes differential pocus prolonged ptt anticoagulation apixaban bleeding bruising cardiac cascade clinical clot clots compressions cpr
How to Evaluate an Abnormal APTT Step 1: Is the PT or APTT Artifactually Prolonged? Step 2: Is
Step 1: Is the PT ... Patient Receiving Anticoagulants ... Heparin, or Direct Thrombin ... Prolonging the PT ... prolonged #diagnosis #hematology
The coagulation cascade is shown, separated into different phases with their endogenous and pharmacological inhibitors shown.
Thrombin, then primes ... and endothelial cells ... #clot #PT #PTT ... diagnosis #models #hematology ... anticoagulation #anticoagulant
This 24M presented with acute onset CP/SOB, hypoxia, HR 150s. What's the diagnosis? Treatment options? Hint:
Thrombus in transit ... Pt had extensive ... later with normal LV ... Echocardiogram #A4C ... PulmonaryEmbolism #Thrombus
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 Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
syndrome • Lupus anticoagulant ... deficiency • Anticoagulants ... warfarin, direct thrombin ... deficiency • Anticoagulant ... Differential #Diagnosis #Hematology
Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
Causes of Abnormal PT ... Prothrombin Time (PT ... heparin - Other anticoagulants ... drugs e.g. direct thrombin ... #differential #hematology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
• Prolonged PT ... • Increased thrombin ... Fibrinogen: ↓ • PT ... Reduction of pro/anticoagulants ... treatment #management #hematology
Cardiac Standstill on POCUS during CPR A 79yo male presents after being found unresponsive by his wife.
ACLS performed x ... lytics in a younger pt ... septal bowing into LV ... dilate to size of LV ... #S4C #Intraarrest
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