18 results
ISTH Scoring System for Disseminated Intravascular Coagulation (DIC)
Platelet count:
 • Expected: Low (or normal)
 • Elevation
• Elevation in thrombin ... platelet aggregation PT ... using INR use PT ... ISTH #Scoring #diagnosis ... #hematology #laboratory
Von Willebrand Disease - Most common inherited bleeding disorder 
Clinical 
 • Easy bruising 
 •
bleeding disorder Clinical ... GI. uterine) Laboratory ... 2B) • Normal PT ... VonWillebrand #Disease #Diagnosis ... #Hematology
Our approach to the diagnosis and initial management of patients with suspected HIT. Our approach is
and initial management ... based primarily on clinical ... results of HIT laboratory ... #Diagnosis #Management ... #Hematology #HIT
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Erythematosus (SLE) - Diagnosis ... 40, F:M 9:1 • Clinical ... versus DIL • Laboratory ... Erythematosus #Diagnosis ... #rheumatology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
• Increased thrombin ... organ damage Clinical ... #Coagulation #diagnosis ... causes #treatment #management ... #hematology
Rheumatoid Arthritis Summary
Overview: chronic, inflammatory symmetric polyarthritis involving small joints of hands/feet, knees, shoulders
Signs & Symptoms:
effusions, reduced ROM Laboratory ... • Ultrasound Diagnosis ... : CLINICAL DIAGNOSIS ... Rheumatoid #Arthritis #diagnosis ... #management #rheumatology
Autoimmune Hepatitis

Clinical Presentation
 - Highly variable clinical presentation, from subclinical disease to acute liver failure.
 -
Highly variable clinical ... Anti-LKM & Anti-ALC ... Hepatitis (eg Viral) Management ... Necrosis) If mild laboratory ... #Management #Hepatology
IgG4-Related Disease
Clinical history:  Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor
4 phenotypes:
 •
Related Disease Clinical ... PET-CT Imaging (→ Diagnostic ... relapse No specific laboratory ... #management #phenotypes ... workup #treatment #rheumatology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Fever is the main clinical ... Hypofibrinogenemia • ↑ PT ... Activation #Syndrome #Diagnosis ... #Management #Hematology ... #Rheumatology
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... calcium-b) • Laboratory ... 40, F:M 9:1 • Clinical ... comparison #table #rheumatology ... #diagnosis #management