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hematology coagulation clinical pocus intransit abnormal anticoagulation aptt causes dic differential disseminated echocardiogram embolism intravascular mcconnells prolonged ptt sign testing
Effect of Anticoagulants on Coagulation Tests PT / INR, aPTT, Anti-Xa Activity, Activated Clotting Time, Thrombin Time,
Effect of Anticoagulants ... Coagulation Tests PT ... Clotting Time, Thrombin ... Anticoagulation #Testing #Diagnosis ... #Laboratory #Effects
Cool echo - RV strain, McConnell sign, and CLOT IN TRANSIT!! BP is normal and pt
McConnell sign, and CLOT ... is normal and pt ... Echocardiogram #A4C ... Pulmonary #Embolism #Thrombus ... #Clots #InTransit
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 ISTH Scoring System for Disseminated Intravascular Coagulation (DIC) Platelet count: • Expected: Low (or normal) • Elevation
platelet aggregation PT ... using INR use PT ... to form clots, ... ISTH #Scoring #diagnosis ... #hematology #laboratory
This 24M presented with acute onset CP/SOB, hypoxia, HR 150s. What's the diagnosis? Treatment options? Hint:
What's the diagnosis ... Thrombus in transit ... Pt had extensive ... Echocardiogram #A4C ... #Clots #InTransit
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 How to Evaluate an Abnormal APTT Step 1: Is the PT or APTT Artifactually Prolonged? Step 2: Is
Step 1: Is the PT ... Patient Receiving Anticoagulants ... Heparin, or Direct Thrombin ... Prolonging the PT ... APTT #prolonged #diagnosis
The coagulation cascade is shown, separated into different phases with their endogenous and pharmacological inhibitors shown.
FVa to generate thrombin ... Thrombin, then primes ... #clot #PT #PTT ... #diagnosis #models ... anticoagulation #anticoagulant
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
- Differential Diagnosis ... deficiency • Anticoagulants ... warfarin, direct thrombin ... deficiency • Anticoagulant ... #Differential #Diagnosis
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
• Increased thrombin ... venipuncture sites Laboratory ... significant fibrin clot ... Reduction of pro/anticoagulants ... #Coagulation #diagnosis
Normal Thromboelastogram - Specific parameters represent the 3 phases of the cell-based model of haemostasis: initiation,
certain level of clot ... formation; i.e. thrombin ... of the fibrin clot ... lysis time (s) #Diagnosis ... Interpretation #Laboratory
Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
Causes of Abnormal PT ... Prothrombin Time (PT ... heparin - Other anticoagulants ... drugs e.g. direct thrombin ... Prolonged #Causes #diagnosis
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