5 results
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Constitutional Syndromes ... and petechiae Causes ... Constitutional Syndromes ... marrow-failure syndromes ... Anemia #oncology #hematology
Major Clinical Trials and Evidence Summary for Transfusion Thresholds in Critical Care

TRICC - NEJM 1999 -
Care TRICC - NEJM ... unnecessary and cause ... /vmoitra) #EBM ... Transfusion #Thresholds #Hematology ... #VisualAbstract
Clinical Trial of Fluid Infusion Rates for Pediatric Diabetic Ketoacidosis - Kupperman et al. NEJM 2018

https://www.nejm.org/doi/full/10.1056/NEJMoa1716816
Study
NEJM 2018 https ... TessaRDavis #EBM ... #VisualAbstract ... #Peds #Pediatrics ... Infusion #Rates #NEJM
Causes of Neutropenia - Differential Diagnosis
Neonate:
 - Infection - by far the most common cause
 -
neutropenia, Kostmann syndrome ... Chediak-Higashi syndrome ... replacing the BM ... white blood cell aplasia ... #hematology
Idiopathic CD4 Lymphopenia (ICL) / Lymphocytopenia 

DIAGNOSTIC CRITERIA FOR ICL
 • Persistent CD4 T-cell lymphopenia
 •
chemotherapy) • Genetic syndromes ... Heme (lymphoma. aplasia ... EBV. CMV. ... ICL #diagnosis #hematology ... #Differential #Causes