9 results
Causes of Thrombocytopenia - Differential Diagnosis Framework
Decreased Production:
 - Drugs (chemo, yang, sulfa, acetaminophen, NSAIDs, quinine,
Causes of Thrombocytopenia ... - Differential ... Viral: HIV, HCV, EBV ... : ITP, HITT - Autoimmune ... antiphospholipid syndrome
Causes of Neutropenia - Differential Diagnosis
Neonate:
 - Infection - by far the most common cause
 -
- Differential ... neutropenia, Kostmann syndrome ... Chediak-Higashi syndrome ... #Neutropenia #differential ... #hematology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Liver Injury - Differential ... Algorithm Vascular Causes ... vein: Budd-chiari syndrome ... HBV, HCV, HEV, EBV ... : Autoimmune hepatitis
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
Vasculitides - Differential ... tract, and often causes ... glomerulonephritis) • Anti-GBM ... mucositis - Rash ... #diagnosis #rheumatology
Causes of Purpura or Easy Bruising in Children

Platelet count reduced, i.e. thrombocytopenia
 - Increased platelet destruction
Causes of Purpura ... erythematosus) - Alloimmune ... Purpura #Bruising #Causes ... #peds #pediatrics ... #diagnosis #differential
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Vasculitis - Differential ... , mucositis • Rash ... tract, and often causes ... pain and GN Anti-GBM ... #Diagnosis #Rheumatology
Idiopathic CD4 Lymphopenia (ICL) / Lymphocytopenia 

DIAGNOSTIC CRITERIA FOR ICL
 • Persistent CD4 T-cell lymphopenia
 •
W/ LOW CD4 • Autoimmune ... chemotherapy) • Genetic syndromes ... EBV. CMV. ... #Differential # ... Causes #lymphocytopenia
Autoimmune Myositis - Differential Diagnosis Framework

Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
- Differential ... Symptoms: • Gottron rash ... • ANA < 20 % IBM ... statins - probably caused ... #differential #
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4)

Work-up of an Elevated Globulin Gap:
•
changes (POEMS syndrome ... acute HIV, HBV, EBV ... Cirrhosis, ETOH, autoimmune ... Gap #ProteinGap #differential ... #diagnosis #hematology