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diagnosis algorithm hepatology thrombocytopenia anemia classification dermatology erythematosus hemolytic hepatitis injury liver lupus management sle vasculitis acute agglutinin bruising cd4
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Causes of Thrombocytopenia ... - Differential ... methotrexate) • Drugs Autoimmune ... Non-lmmune: • HELLP Syndrome ... #Hematology
Causes of Thrombocytopenia - Differential Diagnosis Framework Decreased Production: - Drugs (chemo, yang, sulfa, acetaminophen, NSAIDs, quinine,
Causes of Thrombocytopenia ... Viral: HIV, HCV, EBV ... : ITP, HITT - Autoimmune ... antiphospholipid syndrome ... Diagnosis #Framework #hematology
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
Causes of Thrombocytosis ... - Differential ... disorders (e.g. autoimmune ... Myelodysplastic syndrome ... #hematology #secondary
Elevated Transaminases / Transaminitis - Differential Diagnosis • Infectious: HAV, HCV, HEV, EBV, HSV, CMV •
Transaminitis - Differential ... HAV, HCV, HEV, EBV ... • Autoimmune ... #Diagnosis #causes ... #hepatology
Causes of Hypocomplementemia - CHAMPS Mnemonic C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis H - Heavy Chain deposition
Causes of Hypocomplementemia ... Atypical HUS, autoimmune ... antiphospholipid syndrome ... Mnemonic #diagnosis #differential ... #hematology
Causes of Eosinophilia - Differential Diagnosis Bugs: - Fungus (aspergillosis) - Viral (HIV) - Ectoparasites (scabies, myiasis)
Causes of Eosinophilia ... - Differential ... (vasculitis / autoimmune ... Hypereosinophilic Syndrome ... #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... ) - HELLP syndrome ... Hemolytic uremic syndrome ... #differential # ... diagnosis #hematology
Causes of Fever of Unknown Origin (FUO) - Differential Diagnosis • Infection: Extrapulmonary tuberculosis, Abscess, Endocarditis,
Origin (FUO) - Differential ... Lemierre's syndrome ... Brucellosis, Q fever, EBV ... Malignancy: - Hematologic ... Diseases (e.g. autoimmune
Causes of Neutropenia - Differential Diagnosis Neonate: - Infection - by far the most common cause -
- Differential ... neutropenia, Kostmann syndrome ... Chediak-Higashi syndrome ... #Neutropenia #differential ... #hematology
Causes of Acute Liver Injury - Differential Diagnosis Hepatocellular - Liver Parenchyma • Infectious: Hepatitis C, A,
Causes of Acute ... Liver Injury - Differential ... C, A, E, B, D, EBV ... Other: NAFLD, Autoimmune ... obstruction, HELLP Syndrome
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