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diagnosis disease syndrome lupus vasculitis differential stills adultonset aosd classification druginduced erythematosus giantcell neurology signs symptoms 2ndline activation adult aortitis
Aortitis - Differential Diagnosis Framework Non-Infectious Aortitis: • Vasculitides: Giant Cell Arteritis (GCA), Takayasu's arteritis, Cogan's Syndrome,
(GCA), Takayasu's ... arteritis, Cogan's ... (RA), Systemic ... erythematosus (SLE ... Differential #Diagnosis #rheumatology
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
arteritis (GCA) ... (Cornelia NEJM ... Treatment of GCA ... them, but urgent rheumatology ... Symptoms #Diagnosis #Management
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... Manifestations: Malar rash ... life-threatening • Treatment ... #lupus #Systemic ... #Summary #rheumatology
Behcet's Syndrome - Treatment Ulcers: • Treatment: Topical steroids • Prevention: Colchicine • Azathioprine for refractory disease Arthritis:
Behcet's Syndrome - Treatment ... Ulcers: • Treatment ... refractory disease Arthritis ... #management #pharmacology ... #rheumatology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Constitutional symptoms, Arthritis ... NPSLE rare, Malar rash ... months to years) Systemic ... comparison #table #rheumatology ... #diagnosis #management
Treatment of giant cell arteritis (GCA) 1st Line Strategy - GC 0.7 mg/kg/day, except for: • Aortitis
Treatment of giant ... cell arteritis ... #GCA #Treatment ... #Management #Relapses ... #Indications #rheumatology
Autoimmune Myositis Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
weakness, less systemic ... myositis, and arthritis ... Can also see mechanics ... after 2 years of treatment ... Myositis #diagnosis #rheumatology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Petechial or purpuric rash ... erythematosus [SLE ... Treatment: • Corticosteroids ... Syndrome #Diagnosis #Management ... #Hematology #Rheumatology
Adult-Onset Still's Disease (AOSD) Rare inflammatory disorder of unknown etiology, difficult to diagnose because of heterogenous presentation.
maculopapular rash ... episode (30%) Systemic ... Disease #AOSD #rheumatology ... #diagnosis #management ... #treatment
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Fever, Arthralgia/arthritis ... , Skin rash ± odynophagia ... solid cancers • Systemic ... Disease #diagnosis #management ... #treatment #rheumatology
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