52 results
Plain radiography of the abdomen revealed calcification of both adrenal glands. A homozygous mutation in LIPA
calcification of both adrenal ... acid lipase is critical ... and gut, which causes ... #clincial #peds ... #infant #NEJM #
Major Clinical Trials and Evidence Summary for Transfusion Thresholds in Critical Care

TRICC - NEJM 1999 -
Major Clinical Trials ... Thresholds in Critical ... Transfusing blood ... Blood saves lives ... unnecessary and cause
Vibrio Vulnificus skin infection
Cirrhosis w/recent consumption of raw oysters w/rapidly evolving rash. 
Vibrio vulnificus part of
rapidly evolving rash ... marine microbiota & causes ... , hypotension, rash ... immunosuppressive meds ... dermatology #legs #clinical
Acute Purpura Fulminans Skin Rash on Physical Exam 
60 year old male ITP s/p splenectomy 
1d
Fulminans Skin Rash ... rigors, diarrhea, nausea ... fulminans) and critical ... Your blood cxs identify ... #clinical #photo
Secondary Causes of Hypertension - Differential Diagnosis Algorithm
Hypertension - BP > 140/90 (>130/80 for DM)
Hypertensive urgency
based on repeat clinic ... visits, Ambulatory blood ... multi-drug resistance) Renal ... • Bilateral RAS ... • Unilateral RAS
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis
Baseline Investigations: full blood count with differential,
Investigations: full blood ... osmolarity If cause ... investigations depending on clinical ... screen, including blood ... Diagnosis #nephrology #causes
Approach to Undifferentiated Shock - OnePager Summary
Shock occurs when there is inadequate blood flow (CO) &
is inadequate blood ... ), RV Failure (PE ... Toxins (CCB, BB, BRASH ... Obstruction (HOCM, critical ... Failure, Endocrine (adrenal
Nucleated red blood cells, aka normoblasts or erythroblasts, were released prematurely from the bone marrow in
Nucleated red blood ... fetus/newborn the causes ... #Clinical #Path ... #Peds #BloodSmear ... #Blood #Smear #
Causes of Secondary Hypertension - Workup and Differential Diagnosis
Approach (when evaluation should be done):
1. Severe or
increased lability in blood ... hypertension (blood ... 109 mm Hg) with clinical ... hypertension (blood ... Causes: • Vascular
21-Hydroxylase Deficiency (21-OHD): Pathogenesis and Clinical Findings
Autosomal recessive mutation in CYP21A2 coding for the enzyme 21-OHase
Pathogenesis and Clinical ... enzyme 21-OHase causes ... 21-OHD in the adrenal ... as "congenital adrenal ... endocrinology #peds