25 results
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... 40, F:M 9:1 • Clinical ... Manifestations: Malar rash ... Positive in 60-80% of cases ... Management #Summary #rheumatology
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... NPSLE rare, Malar rash ... 40, F:M 9:1 • Clinical ... Manifestations: Malar rash ... comparison #table #rheumatology
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Clinical Features ... of Systemic Lupus ... Photosensitivity, Butterfly rash ... Thrombocytopenia #Lupus ... symptoms #diagnosis #rheumatology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Manifestations of Systemic Lupus ... Erythematosus (SLE) Clinical ... autoantibodies that will cause ... Diagnosis of Lupus ... CNS #neurology #rheumatology
Major Clinical Trials and Evidence Summary for Transfusion Thresholds in Critical Care

TRICC - NEJM 1999 -
Major Clinical Trials ... Thresholds in Critical ... Care TRICC - NEJM ... unnecessary and cause ... Transfusion #Thresholds #Hematology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... evidence of (fatigue, rash ... Non-autoimmune rheumatologic ... lymphoproliferative syndrome Clinical ... Erythematosus #Diagnosis #Rheumatology
Vibrio Vulnificus skin infection
Cirrhosis w/recent consumption of raw oysters w/rapidly evolving rash. 
Vibrio vulnificus part of
rapidly evolving rash ... marine microbiota & causes ... , hypotension, rash ... immunosuppressive meds ... dermatology #legs #clinical
Plain radiography of the abdomen revealed calcification of both adrenal glands. A homozygous mutation in LIPA
acid lipase is critical ... and gut, which causes ... #clincial #peds ... calcifications #infant #NEJM
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
fever syndromes Clinical ... Fever is the main clinical ... Petechial or purpuric rash ... SJIA], systemic lupus ... #Rheumatology
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
GPA causes disease ... Rarely dominate the clinical ... Maculopapular rash ... #dermatology #rash ... #diagnosis #rheumatology