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diagnosis lupus treatment dermatology sle erythematosus syndrome systemic dermatomyositis druginduced oncology product reactions signs summary symptoms transfusion activation antibody antimda5
Warm Antibody Autoimmune Hemolytic Anemia 1) DIAGNOSE AIHA • Anemia: macrocytic > normocytic, ↑ reticulocytes •
DIAGNOSE AIHA • Anemia ... type ± C3d • Blood ... 2) LOOK FOR a cause ... #diagnosis #management ... #treatment #rheumatology
Major Clinical Trials and Evidence Summary for Transfusion Thresholds in Critical Care TRICC - NEJM 1999 -
Major Clinical Trials ... Transfusing blood ... Blood saves lives ... unnecessary and cause ... Transfusion #Thresholds #Hematology
VEXAS (Vacuoles, E1 enzyme, X-linked, Autoinflammatory, Somatic) Syndrome Clinical Syndrome: • Common Clinical Features: alveolitis, ear and
Somatic) Syndrome Clinical ... Abnormalities: macrocytic anemia ... including peripheral blood ... myeloid cells NEJM ... Autoinflammatory #Somatic #rheumatology
Hematology Algorithms Anemia is described as a reduction in the proportion of the red blood cells.
Hematology Algorithms ... proportion of the red blood ... three peripheral blood ... well as varying clinical ... These causes could
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Clinical Features ... Photosensitivity, Butterfly rash ... Glomerulonephritis Myositis(5%) Blood ... (75%): Anemia ( ... symptoms #diagnosis #rheumatology
Vibrio Vulnificus skin infection Cirrhosis w/recent consumption of raw oysters w/rapidly evolving rash. Vibrio vulnificus part of
marine microbiota & causes ... hemochromatosis, hemolytic anemia ... immunosuppressive meds ... #cellulitis #dermatology ... #legs #clinical
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Diagnosis and Management ... 40, F:M 9:1 • Clinical ... Manifestations: Malar rash ... Positive in 60-80% of cases ... #Summary #rheumatology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Clinical Presentation ... and petechiae Causes ... result from low blood ... #oncology #hematology ... #diagnosis #management
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
GPA causes disease ... Rarely dominate the clinical ... Maculopapular rash ... vasculitis (inflamed blood ... #rheumatology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Fever is the main clinical ... Petechial or purpuric rash ... with leukopenia, anemia ... Syndrome #Diagnosis #Management ... #Hematology #Rheumatology
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